ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
The research on ceramic scaffolds for bone tissue engineering is, nowadays, one of thenewest and most attractive topics in the field of materials for biomedical applications.These scaffolds are aimed to provide supporting or even enhance the reparative capacity ofbody. Biphasic calcium phosphates (BCPs) and silicon doped BCP are very interestingcandidates to be used as materials for scaffolds fabrication in bone tissue engineering.BCPs and silicon doped BCP consist of a mixture of hydroxyapatite (HA) and β-tricalciumphosphate (β-TCP) or HA and α-tricalcium phosphate (α-TCP), respectively. For theregenerative purposes BCPs show better performance than HA because of the highersolubility of β-TCP compound, which facilitate the subsequent bone ingrowth in theimplant. On the other, silicon doped BCP involve silicon that substituted into the apaptitecrystal lattice for phosphorous with the subsequent charge imbalance. HA/α-TCP basedbioceramics exhibits an important improvement of the bioactive behaviour with respect tonon-substituted apatites. This work reviews the procedures to synthesise and fabricatescaffolds based on HA/β-TCP and silicon stabilised HA/α-TCP. Special attraction hasbeen paid in the different synthesis methods and to the shaping of final scaffolds. Byknowing the scaffold features at the crystallinity and macrostuctural level, thebiocompatibility and clinical performance can be better understood, which will be alsoconsidered in this review
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/57/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.377.19.pdf
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