ISSN:
1612-1112
Schlagwort(e):
Capillary electrophoresis
;
4-Hydroxy-2H-1,4-benzoxazin-3(4H)-ones
;
Cyclodextrins
;
Enantioseparation
;
Separation of diastereomers
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Chemie und Pharmazie
Notizen:
Summary A high performance capillary electrophoresis (HPCE) procedure for the enantioseparation of the methyl acetals3 and4 of the natural products DIBOA1 and DIMBOA2, respectively, has been developed using borate buffers (pH 9–10 range), cyclodextrins as chiral additives and addition of up to 20% methanol. A mixture of GDIBOA5 and GDIMBOA6 of natural origin was also clearly separated. HPCE proved to be superior to HPLC by the first separation of GDIBOA5 and three of its diastereomers resulting from a synthetic approach to this acetalglucoside.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF02269838
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