Publication Date:
1983-07-01
Description:
A low molecular weight, lipophilic, copper coordination complex with superoxide dismutase-mimetic activity inhibited biochemical and biological actions of a tumor promoter in mouse epidermis. Such inhibitory effects implicate reactive oxygen species in the tumor promotion process.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kensler, T W -- Bush, D M -- Kozumbo, W J -- ES00454/ES/NIEHS NIH HHS/ -- ES07067/ES/NIEHS NIH HHS/ -- New York, N.Y. -- Science. 1983 Jul 1;221(4605):75-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6857269" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Antineoplastic Agents/*pharmacology
;
Carcinogens/pharmacology
;
Female
;
Mice
;
Ornithine Decarboxylase/metabolism
;
Papilloma/chemically induced
;
Salicylates/pharmacology
;
Skin Neoplasms/chemically induced
;
Superoxide Dismutase/*metabolism
;
Tetradecanoylphorbol Acetate/pharmacology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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