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  • 1
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    Is the acetylcholine receptor a rabies virus receptor? (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-01-08
    Description: Rabies virus was found on mouse diaphragms and on cultured chick myotubes in a distribution coinciding with that of the acetylcholine receptor. Treatment of the myotubes with alpha-bungarotoxin and d-tubocurarine before the addition of the virus reduced the number of myotubes that became infected with rabies virus. These findings together suggest that acetylcholine receptors may serve as receptors for rabies virus. The binding of virus to acetylcholine receptors, which are present in high density at the neuromuscular junction, would provide a mechanism whereby the virus could be locally concentrated at sites in proximity to peripheral nerves facilitating subsequent uptake and transfer to the central nervous system.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lentz, T L -- Burrage, T G -- Smith, A L -- Crick, J -- Tignor, G H -- AI 11132/AI/NIAID NIH HHS/ -- AI 12541/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1982 Jan 8;215(4529):182-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7053569" target="_blank"〉PubMed〈/a〉
    Keywords: Acetylcholine/metabolism ; Acetylcholinesterase/metabolism ; Animals ; Binding, Competitive ; Bungarotoxins/metabolism ; Cells, Cultured ; Chick Embryo ; Diaphragm ; Mice ; Microscopy, Electron ; Neuromuscular Junction/*metabolism ; Rabies virus/*metabolism ; Receptors, Cholinergic/*metabolism ; Receptors, Virus/*metabolism ; Tubocurarine/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
    Electronic Resource
    Electronic Resource
    Formation of sarcomeres in the embryonic heart of the lobster (1979)
    Springer
    Cell & tissue research 198 (1979), S. 477-486 
    Details
    ISSN: 1432-0878
    Keywords: Embryonic heart ; Myogenesis ; Sarcomere ; Crustacea (Homarus americanus) ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Cardiomyoblasts in the myocardium of embryonic lobsters at 3–4 weeks and 6 months of development were examined with the transmission electron microscope in order to describe the events in the formation of sarcomeres in a neurogenic cardiac system. Thick and thin myofilaments appear first in the cell periphery near the sarcolemma. They align in parallel in a sequential fashion to form consecutive sarcomeric units. Well-defined A and I bands appear before any semblance of a Z line is present. The initial sarcomere is anchored to the sarcolemma by the insertion of thin myofilaments into a region of electron dense material associated intimately with the sarcolemma. Myofibrils grow outward in several planes away from the electron-dense regions of membrane that serve as focal points for myofibril formation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234192
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  • 3
    Electronic Resource
    Electronic Resource
    Cellular organization of the embryonic lobster heart (1978)
    Springer
    Cell & tissue research 188 (1978), S. 171-187 
    Details
    ISSN: 1432-0878
    Keywords: Embryonic heart ; Crustacea (Homarus americanus) ; Cardiac muscle ; Intercellular junctions ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The cellular organization of the embryonic heart of the lobster Homarus americanus was examined in 6-week and 6-month-old animals. The heart wall consists of an outer adventitial layer of fibroblast cells and an inner layer of transversely striated myocardial cells. Present in close association with the myocardium are cardiac neurons, hemocytes and so-called storage cells. Adjacent fibroblasts form fasciae adhaerentes and gap junctions. Adherent junctions also occur between fibroblasts and myocardial cells. Intercalated discs and differentiated membrane regions of close apposition (4 nm) occur between adjacent myocardial cells. The cardiac neurons form a ganglion that contains four small and five large somata. Regions of neuropil are present. Motor axons arising from the cardiac ganglion form neuromuscular synapses with the myocardial cells. The storage cells contain large inclusions and form gap junctions with the myocardial cells. They may supply nutritive material to the developing myocardium. The heart at 6 weeks is about 200 μm long and 160 μm wide. At 6 months, it is about 300 μm long and 250 μm wide. The myocardium at 6 weeks is one cell layer thick, and the cells are from 2–6 μm in maximum width. At 6 months the myocardium is 2–4 cells thick, and the cells are from 6–12 μm in width. Therefore, the myocardium grows by an increase in the number and size of the myocardial cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00222629
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  • 4
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    Foot-and-mouth disease virus particles contain replicase protein 3D. (1994)
    National Academy of Sciences
    Details
    Publication Date: 1994-01-18
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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