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  • 1
    Publication Date: 2016-01-09
    Description: A rich elasmobranch assemblage was recovered from the early Eocene (Ypresian) Fishburne Formation in a limestone quarry at Jamestown, Berkeley County, South Carolina, USA. Reported herein are 22 species belonging to 8 orders, at least 15 families, and 21 genera. It includes the first occurrence of Protoginglymostoma from North America. Many of the reported species have large palaeobiogeographical ranges and inhabited waters on both sides of the Atlantic, whereas others were endemic to the east coast of North America. The paucity of sizeable dentition from several of the larger species in this assemblage, and the apparent absence of relatively large macrophagous species found in contemporaneous deposits elsewhere, suggests the Jamestown site may represent a nursery ground and refuge for young and smaller individuals.
    Print ISSN: 0008-4077
    Electronic ISSN: 1480-3313
    Topics: Geosciences
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  • 2
    Publication Date: 2014-12-31
    Description: Interactions between natural killer (NK) cells and dendritic cells (DCs) aid DC maturation and promote T-cell responses. Here, we have analyzed the response of human NK cells to tumor cells, and we identify a pathway by which NK–DC interactions occur. Gene expression profiling of tumor-responsive NK cells identified the very...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 3
    Publication Date: 2009-11-06
    Description: Redox processes are at the heart of numerous functions in chemistry and biology, from long-range electron transfer in photosynthesis and respiration to catalysis in industrial and fuel cell research. These functions are accomplished in nature by only a limited number of redox-active agents. A long-standing issue in these fields is how redox potentials are fine-tuned over a broad range with little change to the redox-active site or electron-transfer properties. Resolving this issue will not only advance our fundamental understanding of the roles of long-range, non-covalent interactions in redox processes, but also allow for design of redox-active proteins having tailor-made redox potentials for applications such as artificial photosynthetic centres or fuel cell catalysts for energy conversion. Here we show that two important secondary coordination sphere interactions, hydrophobicity and hydrogen-bonding, are capable of tuning the reduction potential of the cupredoxin azurin over a 700 mV range, surpassing the highest and lowest reduction potentials reported for any mononuclear cupredoxin, without perturbing the metal binding site beyond what is typical for the cupredoxin family of proteins. We also demonstrate that the effects of individual structural features are additive and that redox potential tuning of azurin is now predictable across the full range of cupredoxin potentials.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149807/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149807/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marshall, Nicholas M -- Garner, Dewain K -- Wilson, Tiffany D -- Gao, Yi-Gui -- Robinson, Howard -- Nilges, Mark J -- Lu, Yi -- 5 T32 GM070421/GM/NIGMS NIH HHS/ -- T32 GM070421/GM/NIGMS NIH HHS/ -- England -- Nature. 2009 Nov 5;462(7269):113-6. doi: 10.1038/nature08551.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Chemistry, University of Illinois, Urbana-Champaign, Illinois 61801, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19890331" target="_blank"〉PubMed〈/a〉
    Keywords: Azurin/*chemistry/genetics/*metabolism ; Binding Sites ; Copper/metabolism ; Crystallography, X-Ray ; Hydrogen Bonding ; Hydrophobic and Hydrophilic Interactions ; Models, Molecular ; Mutant Proteins/chemistry/genetics/metabolism ; Mutation ; Oxidation-Reduction ; Protein Conformation
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 4
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2006-09-02
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wilson, Timothy D -- New York, N.Y. -- Science. 2006 Sep 1;313(5791):1251-2.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Psychology, University of Virginia, Charlottesville, VA 22904-4400, USA. tdw@virginia.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16946061" target="_blank"〉PubMed〈/a〉
    Keywords: *Achievement ; Adolescent ; African Americans/*psychology ; Educational Measurement ; *Educational Status ; Humans ; *Psychology, Social ; *Self Concept ; *Social Perception ; Social Values
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2007-09-08
    Description: All animals can predict the hedonic consequences of events they've experienced before. But humans can predict the hedonic consequences of events they've never experienced by simulating those events in their minds. Scientists are beginning to understand how the brain simulates future events, how it uses those simulations to predict an event's hedonic consequences, and why these predictions so often go awry.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gilbert, Daniel T -- Wilson, Timothy D -- R01-MH56075/MH/NIMH NIH HHS/ -- New York, N.Y. -- Science. 2007 Sep 7;317(5843):1351-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Psychology, 33 Kirkland Street, Harvard University, Cambridge, MA 02138, USA. gilbert@wjh.harvard.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17823345" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Brain/physiology ; Humans ; Imagination ; Intention ; Mental Processes/*physiology ; Motivation ; Perception/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2008-08-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wilson, Timothy D -- Bar-Anan, Yoav -- New York, N.Y. -- Science. 2008 Aug 22;321(5892):1046-7. doi: 10.1126/science.1163029.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉University of Virginia, Charlottesville, VA 22904-4400, USA. twilson@virginia.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/18719269" target="_blank"〉PubMed〈/a〉
    Keywords: Attitude ; *Decision Making ; Humans ; *Mental Processes ; Politics ; *Unconscious (Psychology)
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
    Publication Date: 2009-03-21
    Description: Two experiments revealed that (i) people can more accurately predict their affective reactions to a future event when they know how a neighbor in their social network reacted to the event than when they know about the event itself and (ii) people do not believe this. Undergraduates made more accurate predictions about their affective reactions to a 5-minute speed date (n = 25) and to a peer evaluation (n = 88) when they knew only how another undergraduate had reacted to these events than when they had information about the events themselves. Both participants and independent judges mistakenly believed that predictions based on information about the event would be more accurate than predictions based on information about how another person had reacted to it.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gilbert, Daniel T -- Killingsworth, Matthew A -- Eyre, Rebecca N -- Wilson, Timothy D -- New York, N.Y. -- Science. 2009 Mar 20;323(5921):1617-9. doi: 10.1126/science.1166632.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Psychology, Harvard University, Cambridge, MA 02138, USA. gilbert@wjh.harvard.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19299622" target="_blank"〉PubMed〈/a〉
    Keywords: *Affect ; *Emotions ; Female ; *Forecasting ; Happiness ; Humans ; Male ; Peer Group ; *Social Perception
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2013-01-05
    Description: We measured the personalities, values, and preferences of more than 19,000 people who ranged in age from 18 to 68 and asked them to report how much they had changed in the past decade and/or to predict how much they would change in the next decade. Young people, middle-aged people, and older people all believed they had changed a lot in the past but would change relatively little in the future. People, it seems, regard the present as a watershed moment at which they have finally become the person they will be for the rest of their lives. This "end of history illusion" had practical consequences, leading people to overpay for future opportunities to indulge their current preferences.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Quoidbach, Jordi -- Gilbert, Daniel T -- Wilson, Timothy D -- P01 AG020166/AG/NIA NIH HHS/ -- New York, N.Y. -- Science. 2013 Jan 4;339(6115):96-8. doi: 10.1126/science.1229294.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉National Fund for Scientific Research, Brussels, Belgium.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23288539" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Adult ; Aged ; Female ; *Forecasting ; History ; Humans ; *Illusions ; Male ; Middle Aged ; Personality ; Self Report ; *Time Perception ; Young Adult
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
    Publication Date: 2014-07-06
    Description: In 11 studies, we found that participants typically did not enjoy spending 6 to 15 minutes in a room by themselves with nothing to do but think, that they enjoyed doing mundane external activities much more, and that many preferred to administer electric shocks to themselves instead of being left alone with their thoughts. Most people seem to prefer to be doing something rather than nothing, even if that something is negative.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330241/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330241/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wilson, Timothy D -- Reinhard, David A -- Westgate, Erin C -- Gilbert, Daniel T -- Ellerbeck, Nicole -- Hahn, Cheryl -- Brown, Casey L -- Shaked, Adi -- T32 MH020006/MH/NIMH NIH HHS/ -- New York, N.Y. -- Science. 2014 Jul 4;345(6192):75-7. doi: 10.1126/science.1250830.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Psychology, University of Virginia, Charlottesville, VA, USA. tdw@virginia.edu. ; Department of Psychology, University of Virginia, Charlottesville, VA, USA. ; Department of Psychology, Harvard University, Cambridge, MA, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24994650" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Adult ; Aged ; Attention ; Electroshock/psychology ; Humans ; Loneliness/*psychology ; Middle Aged ; *Pleasure ; *Thinking ; Young Adult
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
    Publication Date: 2016-03-05
    Description: A paper from the Open Science Collaboration (Research Articles, 28 August 2015, aac4716) attempting to replicate 100 published studies suggests that the reproducibility of psychological science is surprisingly low. We show that this article contains three statistical errors and provides no support for such a conclusion. Indeed, the data are consistent with the opposite conclusion, namely, that the reproducibility of psychological science is quite high.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gilbert, Daniel T -- King, Gary -- Pettigrew, Stephen -- Wilson, Timothy D -- New York, N.Y. -- Science. 2016 Mar 4;351(6277):1037. doi: 10.1126/science.aad7243.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Harvard University, Cambridge, MA, USA. gilbert@wjh.harvard.edu. ; Harvard University, Cambridge, MA, USA. ; University of Virginia, Charlottesville, VA, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/26941311" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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