ISSN:
0021-9304
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
,
Technology
Notes:
Teflon implants containing a single cylindrical pore were surgically embedded in the femural bones of rabbits. A total of eight different pore sizes were used for each experimental animal. Their diameters ranged from 274 to 670 μm, with approximately 50 μm intervals between sizes. The amount of bone tissue ingression and its spatial distribution was assessed for each pore diameter at weekly intervals over a sixteen-week period by bone labeling with Tetracycline injection. From these data an optimum pore diameter of between 400 to 450 μm was observed for maximum bone ingression. The distribution of new bone growth was characterized as an apposition pattern which emanated from the walls and the open end of the pore. No rejection phenomena were observed at the Teflon tissue interfaces.
Additional Material:
7 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jbm.820080608
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