Publication Date:
2014-01-08
Description:
Article The protein thioredoxin regulates the activity of many signalling molecules. Here, Hwang et al. report structural and biochemical evidence that the interaction between thioredoxin and its inhibitor thioredoxin-interacting protein is regulated by a redox-dependent disulphide bond-switching mechanism. Nature Communications doi: 10.1038/ncomms3958 Authors: Jungwon Hwang, Hyun-Woo Suh, Young Ho Jeon, Eunha Hwang, Loi T. Nguyen, Jeonghun Yeom, Seung-Goo Lee, Cheolju Lee, Kyung Jin Kim, Beom Sik Kang, Jin-Ok Jeong, Tae-Kwang Oh, Inpyo Choi, Jie-Oh Lee, Myung Hee Kim
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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