ISSN:
1434-4475
Schlagwort(e):
Keywords. Linalool; Enzymatic resolution; tert-Alcohol; Linalyl acetate hydrolase.
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Chemie und Pharmazie
Notizen:
Summary. Biocatalytic resolution of the tertiary terpene alcohol (±)-linalool was accomplished via hydrolysis of its corresponding acetate ester using two highly enantiospecific enzymes (E 〉 100). The latter were identified in a crude cell-free extract of Rhodococcus ruber DSM 43338 and could be separated by (partial) protein purification. Since they showed opposite enantiopreference, they were termed (R)- and (S)-linalyl acetate hydrolase (LAH). The activity and selectivity of the enzyme preparations was markedly dependent on the fermentation conditions.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/s007060070092
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