ISSN:
0006-3525
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The synthess of 18 co-oligopeptides of L-methionine and glycine is reported. A series of oligomers, Boc-Gly-Metn-OMe (n = 1-6), and six hexamers-containing five methionyl and one glycyl residue were synthesized using the mixed anhydride procedure. Polarimetric studies give evidence that oligomers in the Boc-Gly-Metn-Ome series are essentially disordered in hexafluoroacetone sesquihydrate but begin forming secondry structures at n 〉 4 in trifluorethanol. Difference in the molar rotation values found for the six hexamers in hexafluoroacetone sesquihydrate may indicate that these compounds, while primirily disordered, are present in slightly different conformations.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bip.1978.360170913
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