Publication Date:
2020-08-21
Description:
Background The present study was designed to test the hypothesis that in the liver, excessive fat accumulation impairs cholesterol metabolism mainly by altering the low-density lipoprotein-receptor (LDL-R) pathway. Method Young male Wistar rats were fed standard (SD), high fat (HFD; 60% kcal) or Western (WD; 40% fat + 35% sucrose (17.5% fructose)) diets for 2 or 6 weeks. Results Weight gain (~ 40 g) was observed only following 6 weeks of the obesogenic diets (P
Electronic ISSN:
1476-511X
Topics:
Biology
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