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  • 1
    Electronic Resource
    Electronic Resource
    3,5-Dichlorotyrosines. Preparation of D and L forms (1968)
    s.l. : American Chemical Society
    The @journal of organic chemistry 33 (1968), S. 1665-1666 
    Details
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jo01268a086
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  • 2
    Electronic Resource
    Electronic Resource
    Examination of a Potential Upper Limit to Cardiac Muscle Hypertrophy (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 752 (1995), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1995.tb17433.x
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  • 3
    Electronic Resource
    Electronic Resource
    Intestinal Transport of Cystine Analogues (1965)
    [s.l.] : Nature Publishing Group
    Nature 207 (1965), S. 418-419 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Everted sacs were prepared from the small intestine of adult hamsters of both sexes (3 sacs per animal)4. The serosal or inner portion of the sac was filled with 1 ml. of solution identical in composition to the 5 ml. of outer or mucosal solution. Krebs-Henseleit pH. 7-4 buffer was utilized, ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/207418a0
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  • 4
    Electronic Resource
    Electronic Resource
    Simple theory of transfusions (1965)
    Springer
    Bulletin of mathematical biology 27 (1965), S. 9-20 
    Details
    ISSN: 1522-9602
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract A transfusion can be hypothesized to be required when a determination factor (D=probability of adverse effects if transfusion not given/adverse effects if transfusion is given) exceeds some predetermined value.D varies between the limits 0 and ∞, and in most clinical situations will be a small number on the order of 20. Since the probabilities contributing to the denominator ofD are essentially independent of each other, they can be summed to obtain the probability of ill effects. A method of handling an exception to this, the incompatibility reactions following multiple transfusions within a short time interval, is pointed out. The probability of adverse effects if a transfusion is not given is more difficult to evaluate; values gathered from the literature are presented, as well as methods for obtaining further data. Two techniques for estimating future transfusion requirements are discussed. One is a correlative procedure, which functions by analyzing similar cases admitted to the hospital. The second procedure is an estimate of stability (homeostasis), based on a parameter introduced by B. C. Patten (Scince,134, 1010–1011, 1961). The dilution of endogenous cells and plasma by transfusions is considered and the consequences of many small transfusions compared with those of few (and larger) transfusions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02476464
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  • 5
    Electronic Resource
    Electronic Resource
    Reaction of amines and amino acids with aqueous and nonaqueous acid-ninhydrin (1964)
    Springer
    Microchimica acta 52 (1964), S. 1144-1150 
    Details
    ISSN: 1436-5073
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung In Abwesenheit von Wasser wirkt Ninhydrin in Eisessig auf eine Reihe von Aminosäuren sowie auf Amine und Iminosäuren unter Farbentwicklung ein, so daß das Reagens nicht als spezifisch für Iminosäuren angesehen werden kann. Selbst geringe Mengen Wasser beeinflussen die Reaktion, unterdrücken die Farbentwicklung oder ändern den Farbton. Mit Ninhydrin entwickelte Flecken in Papierchromatogrammen können mit Ninhydrin in Eisessig extrahiert werden und die erhaltenen Färbungen eignen sich für die Erkennung kleiner Stoffmengen.
    Abstract: Résumé En milieu anhydre, la ninhydrine dans l'acide acétique glacial réagit avec un certain nombre d'amino-acides ainsi qu'avec les amines et les iminoacides en donnant des colorations discernables. Dans ces circonstances, on ne peut donc pas considérer le réactif comme spécifique des imino-acides. On a fait ressortir l'influence de l'eau en petite quantité sur la réaction et l'on a remarqué que certains composés donnaient une coloration (ou pas) en milieu aqueux et une autre à sec. Sur les chromatogrammes sur papier on peut éluer en ninhydrine-acide, les taches qui ont réagi avec la ninhydrine et l'on peut utiliser pour les identifications micro-analytiques la coloration qui apparaît.
    Notes: Summary Under anhydrous conditions, ninhydrin in glacial acetic acid reacts with a number of amino acids, as well as amines and imino acids, to produce discernible colors. Hence, the reagent cannot be considered specific for imino acids under such circumstances. The effect of a small amount of water on the reaction was stressed, and some compounds were noted to produce one color (or none) when in aqueous solution, and another color when dry. Ninhydrin-reacted spots on paper chromatograms can be eluted into acid-ninhydrin, and the color produced may be useful in microanalytic identifications.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01224584
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  • 6
    Electronic Resource
    Electronic Resource
    Rapid increase in fraction of cardiac output to bone in experimental calcium deficiency (1969)
    Springer
    Calcified tissue international 3 (1969), S. 17-29 
    Details
    ISSN: 1432-0827
    Keywords: Bone blood flow ; Calcium deficiency ; Metabolic bone disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Description / Table of Contents: Résumé La fraction du débit cardiac destinée á l'os a été étudiée chez des rats jeunes soumis à un régime pauvre en calcium, suivant la méthode86Rb de Sapirstein. Les résultats d'une telle étude montrent bien une augmentation rapide et consistante du débit sanguin destiné aux deux fémurs de ces rats vis à vis des controles. L'hyperhémie osseuse est mise en évidence en même temps que l'on note des modifications importantes de la densité, du pois sec et du contenu en cendre. Le retour à la normalité se fait neuf jours après et ceci malgré la continuation de la diete pauvre, en calcium.
    Abstract: Zusammenfassung Der dem Knochen zufließende Anteil des Herzminutenvolumens bei calciumarmer Ernährung wurde bei der unreifen Ratte mittels der86Rb-Methode vonSapierstein untersucht. Die Resultate dieser Studie zeigten, daß bei calciumuntererährten Ratten im Vergleich zu der Kontrollpopulation eine schnelle und signifikante Zunahme des Minutenvolumenanteils, der dem Oberschenkelknochen zugeführt wird, auftritt. Diese Zunahme findet in derselben Zeitspanne statt, in der auch deutlich sichtbare Veränderungen der Dichte, des Trockengewichtes und des Aschengehaltes festgestellt werden konnten. Der erhöhte Anteil des zum Femur ausgestoßenen Minutenvolumens normalisierte sich nach 9 Tagen, obwohl die calciumarme Diät beibehalten wurde.
    Notes: Abstract The fractional redistribution of cardiac output to bone in dietary calcium deficiency was studied in the immature rat, utilizing the86Rb method of Sapirstein. The results of the study indicated that there was a rapid and significant increase in the fraction of cardiac output to the femurs of the calcium-deficient rats relative to the control population. The increase in cardiac output fraction to bone occurred during the same general time period in which significant changes in the density, dry weight and ash content were detected. The increased fraction of the cardiac output to the femur in the calcium-deficient rats returned to normal after nine days, in spite of continuation of the calcium-deficient diet.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02058642
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  • 7
    Electronic Resource
    Electronic Resource
    Amino acid uptake inAcetabularia (1968)
    Springer
    Protoplasma 66 (1968), S. 255-259 
    Details
    ISSN: 1615-6102
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary 1. Acetabularia accumulated radiolabeled amino acids added to sterile Erd-Schreiber medium. This occured with a variety of amino acids: monoaminomonocarboxylic (glycine), diaminodicarboxylic (L-cystine), monoaminodicarboxylic (L-glutamic acid), diaminomonocarboxylic (L-arginine), and an imino acid (L-proline). 2. After correction for the protein-bound fraction, there was still a considerable quantity of “free” radiolabeled amino acid withinAcetabularia. Additional evidence for the active transport of glycine included a marked temperature dependence as well as sensitivity to-10−3 M cyanide. 3. For at least 21 days following enucleation ofAcetabularia, there was no diminution in glycine transport. Actinomycin D (50 μ/ml) had a minimal effect on transport (7% inhibition). These results suggest that amino acid transport byAcetabularia is either an extranuclear event, or that the nuclear information, once impressed on the organism, has a long persistence.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01252536
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  • 8
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    Physical basis for Haase's law of fetal growth (1970)
    Elsevier
    Details
    Publication Date: 1970-03-01
    Print ISSN: 0022-5193
    Electronic ISSN: 1095-8541
    Topics: Biology
    Published by Elsevier
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  • 9
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    A blood volume heart weight relationship (1967)
    Elsevier
    Details
    Publication Date: 1967-12-01
    Print ISSN: 0022-5193
    Electronic ISSN: 1095-8541
    Topics: Biology
    Published by Elsevier
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  • 10
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    Reaction of amines and amino acids with aqueous and nonaqueous acid-ninhydrin (1964)
    Springer
    Details
    Publication Date: 1964-11-01
    Print ISSN: 0026-3672
    Electronic ISSN: 1436-5073
    Topics: Chemistry and Pharmacology
    Published by Springer
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