ISSN:
1573-0778
Keywords:
drug resistance
;
lung resistance-related protein
;
multidrug resistance
;
multidrug resistance protein
;
P-glycoprotein
;
vaults
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
,
Process Engineering, Biotechnology, Nutrition Technology
Notes:
Abstract In this review we analyze the data supporting the notion that vault-related MDR, as reflected by LRP/MVP overexpression, represents a marker of drug resistance in vitro and in the clinic. Vaults, besides playing a fundamental biological role, may be involved in a novel mechanism of MDR.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1008004502861
Permalink