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  • 1
    Publication Date: 2014-12-31
    Description: The structural elasticity of metal–organic frameworks (MOFs) is a key property for their functionality. Here, we show that 2D IR spectroscopy with pulse-shaping techniques can probe the ultrafast structural fluctuations of MOFs. 2D IR data, obtained from a vibrational probe attached to the linkers of UiO-66 MOF in low concentration,...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 2
    Publication Date: 2011-06-22
    Description: We present whole-genome assemblies of four divergent Arabidopsis thaliana strains that complement the 125-Mb reference genome sequence released a decade ago. Using a newly developed reference-guided approach, we assembled large contigs from 9 to 42 Gb of Illumina short-read data from the Landsberg erecta (Ler-1), C24, Bur-0, and Kro-0 strains, which have been sequenced as part of the 1,001 Genomes Project for this species. Using alignments against the reference sequence, we first reduced the complexity of the de novo assembly and later integrated reads without similarity to the reference sequence. As an example, half of the noncentromeric C24 genome was covered by scaffolds that are longer than 260 kb, with a maximum of 2.2 Mb. Moreover, over 96% of the reference genome was covered by the reference-guided assembly, compared with only 87% with a complete de novo assembly. Comparisons with 2 Mb of dideoxy sequence reveal that the per-base error rate of the reference-guided assemblies was below 1 in 10,000. Our assemblies provide a detailed, genomewide picture of large-scale differences between A. thaliana individuals, most of which are difficult to access with alignment-consensus methods only. We demonstrate their practical relevance in studying the expression differences of polymorphic genes and show how the analysis of sRNA sequencing data can lead to erroneous conclusions if aligned against the reference genome alone. Genome assemblies, raw reads, and further information are accessible through http://1001genomes.org/projects/assemblies.html.
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 3
    Publication Date: 2011-01-04
    Description: In the budding yeast Saccharomyces cerevisiae, self-recognition and the thereby promoted aggregation of thousands of cells into protective flocs is mediated by a family of cell-surface adhesins, the flocculins (Flo). Based on this social behavior FLO genes fulfill the definition of “greenbeard” genes, which direct cooperation toward other carriers of the same gene. The process of flocculation plays an eminent role in the food industry for the production of beer and wine. However, the precise mode of flocculin-mediated surface recognition and the exact structure of cognate ligands have remained elusive. Here, we present structures of the adhesion domain of a flocculin complexed to its cognate ligands derived from yeast high-mannose oligosaccharides at resolutions up to 0.95 Å. Besides a PA14-like architecture, the Flo5A domain reveals a previously undescribed lectin fold that utilizes a unique DcisD calcium-binding motif for carbohydrate binding and that is widely spread among pro- and eukaryotes. Given the high abundance of high-mannose oligosaccharides in yeast cell walls, the Flo5A structure suggests a model for recognition, where social non-self- instead of unsocial self-interactions are favored.
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 4
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2011-09-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ott, Sascha -- New York, N.Y. -- Science. 2011 Sep 23;333(6050):1714-5. doi: 10.1126/science.1211021.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Photochemistry and Molecular Science, Uppsala University, 75120 Uppsala, Sweden. sascha.ott@fotomol.uu.se〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21940885" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
    Publication Date: 2014-02-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ott, Sascha -- Hebenstreit, Daniel -- England -- Nature. 2014 Feb 20;506(7488):295. doi: 10.1038/506295b.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉University of Warwick, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24553233" target="_blank"〉PubMed〈/a〉
    Keywords: *Peer Review, Research ; Volunteers/*statistics & numerical data
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 6
    Publication Date: 2013-04-03
    Description: When an accretion disc falls prey to the runaway instability, a large portion of its mass is devoured by the black hole within a few dynamical times. Despite decades of effort, it is still unclear under what conditions such an instability can occur. The technically most advanced relativistic simulations to date were unable to find a clear sign for the onset of the instability. In this work, we present three-dimensional relativistic hydrodynamics simulations of accretion discs around black holes in dynamical space–time. We focus on the configurations that are expected to be particularly prone to the development of this instability. We demonstrate, for the first time, that the fully self-consistent general relativistic evolution does indeed produce a runaway instability.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
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  • 7
    Publication Date: 2013-03-06
    Description: Newly developed high-speed, synchrotron-based X-ray computed microtomography enabled us to directly image pore-scale displacement events in porous rock in real time. Common approaches to modeling macroscopic fluid behavior are phenomenological, have many shortcomings, and lack consistent links to elementary pore-scale displacement processes, such as Haines jumps and snap-off. Unlike the...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 8
    Publication Date: 2016-11-17
    Description: During the merger of a black hole and a neutron star, baryonic mass can become unbound from the system. Because the ejected material is extremely neutron-rich, the r-process rapidly synthesizes heavy nuclides as the material expands and cools. In this work, we map general relativistic models of black hole–neutron star mergers into a Newtonian smoothed particle hydrodynamics (SPH) code and follow the evolution of the thermodynamics and morphology of the ejecta until the outflows become homologous. We investigate how the subsequent evolution depends on our mapping procedure and find that the results are robust. Using thermodynamic histories from the SPH particles, we then calculate the expected nucleosynthesis in these outflows while varying the level of neutrino irradiation coming from the post-merger accretion disc. We find that the ejected material robustly produces r-process nucleosynthesis even for unrealistically high neutrino luminosities, due to the rapid velocities of the outflow. None the less, we find that neutrinos can have an impact on the detailed pattern of the r-process nucleosynthesis. Electron neutrinos are captured by neutrons to produce protons while neutron capture is occurring. The produced protons rapidly form low-mass seed nuclei for the r-process. These low-mass seeds are eventually incorporated into the first r-process peak at A ~ 78. We consider the mechanism of this process in detail and discuss if it can impact galactic chemical evolution of the first peak r-process nuclei.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
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  • 9
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    PANGAEA
    In:  Supplement to: Devey, Colin W; Ackermand, Dietrich; Binard, Nicolas; Chmarzynski, P; Franke-Bruckmaier, B; Geldmacher, Jörg; Graupner, T; Haake, F W; Haase, Karsten M; Hemond, Christophe; Krüger, O; Mühlhan, Norbert; O'Connor, John; Ott, S; Peucker-Ehrenbrink, Bernhard; Pototzki, Frank; Segl, Monika; Tichomirov, W (1993): Cruise report SO-84: The St Helena hotspot - Las Palmas-Cape Town 02.01.93-20.02.93. Berichte - Reports, Geologisch-Paläontologisches Institut und Museum, Christian-Albrechts-Universität, Kiel; 64; 1-103; ISSN 0175-9302, TIB - Technische Informationsbibliothek Universitätsbibliothek Hannover, Berichte-Reports, Geologisch-Paläontologisches Institut der Universität Kiel, 64, 103 pp, https://doi.org/10.2312/reports-gpi.1993.64
    Publication Date: 2024-02-03
    Description: The SO-84 cruise from Las Palmas to Cape Town studied the underwater volcanism associated with the St Helena hotspot. Wide-spaced grid mapping of a region south and west of St Helena island identified three previously unknown hotspot volcanoes (which we named Josephine 16°27'S-9°W, Jade 16°13'S-7°46'W and Benjamin 16°12'S-8°31'W) and several older, probably near-ridge-generated seamounts. The newly discovered hotspot seamounts, and the previously-known seamounts of Bagration, Bonaparte and Kutuzov were mapped and sampled. Onboard geochemical studies confirm that they all show trace-element (Rb, Nb, Y, Zr, Sr) enriched, hotspot magma-type compositions. Morphological studies and the state of the samples collected from the seamounts (all have at least 1 mm-thick Mn crusts) suggest that none of the volcanoes is presently active, and that the St Helena hotspot is probably extinct at the present time. Josephine appears to be the youngest volcano, and one dredge here yielded fossil hydrothermal material (Fe-hydroxides). To test the hypothesis that the extinction of the hotspot is due to its magmas being channelled to the Mid-Atlantic Ridge, several dredges were taken on the ridge opposite St Helena. Furthermore, in the proposed influence zone of the St Helena plume head, Grattan seamount (9°44'S-12°48'W) was also sampled to examine whether its composition has been affected by the St Helena plume. During the transit from Las Palmas to St Helena, several sediment cores were taken in 3000 m water depth close to the ridge axis for palaeoclimatological work.
    Keywords: 12DS; 13DS; 14DS; 1DS; 20DS; 21DS; 22DS; 23DS; 24DS; 25DS; 26DS; 27DS; 31DS; 35DS; 37DS; 42DS; 43DS; 44DS; 47DS; 49DS; 53DS; 54DS; 55DS; 59DS; 60DS; 63DS; 64DS; 65DS; 68DS; 69DS; 71DS; 72DS; 74DS; 7DS; 83DS; Comment; Deposit type; DEPTH, sediment/rock; Description; Dredge; DRG; Event label; GIK/IfG; GIK17835-1; GIK17841-1; GIK17846-1; GIK17847-1; GIK17848-1; GIK17854-1; GIK17855-1; GIK17856-1; GIK17857-1; GIK17858-1; GIK17859-1; GIK17860-1; GIK17861-1; GIK17865-1; GIK17869-1; GIK17871-1; GIK17876-1; GIK17877-1; GIK17878-1; GIK17881-1; GIK17883-1; GIK17887-1; GIK17888-1; GIK17889-1; GIK17893-1; GIK17894-1; GIK17897-1; GIK17898-1; GIK17899-1; GIK17902-1; GIK17903-1; GIK17905-1; GIK17906-1; GIK17908-1; GIK17917-1; Identification; Institute for Geosciences, Christian Albrechts University, Kiel; NOAA and MMS Marine Minerals Geochemical Database; NOAA-MMS; Position; Quantity of deposit; Sediment type; Size; SO84; Sonne; South Atlantic; ST. HELENA HOTSPOT; Substrate type; Visual description
    Type: Dataset
    Format: text/tab-separated-values, 725 data points
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  • 10
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Structural Biology 104 (1990), S. 63-69 
    ISSN: 1047-8477
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
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