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  • 1
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    Patrolling monocytes control tumor metastasis to the lung (2015)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2015-10-24
    Description: The immune system plays an important role in regulating tumor growth and metastasis. Classical monocytes promote tumorigenesis and cancer metastasis, but how nonclassical "patrolling" monocytes (PMo) interact with tumors is unknown. Here we show that PMo are enriched in the microvasculature of the lung and reduce tumor metastasis to lung in multiple mouse metastatic tumor models. Nr4a1-deficient mice, which specifically lack PMo, showed increased lung metastasis in vivo. Transfer of Nr4a1-proficient PMo into Nr4a1-deficient mice prevented tumor invasion in the lung. PMo established early interactions with metastasizing tumor cells, scavenged tumor material from the lung vasculature, and promoted natural killer cell recruitment and activation. Thus, PMo contribute to cancer immunosurveillance and may be targets for cancer immunotherapy.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hanna, Richard N -- Cekic, Caglar -- Sag, Duygu -- Tacke, Robert -- Thomas, Graham D -- Nowyhed, Heba -- Herrley, Erica -- Rasquinha, Nicole -- McArdle, Sara -- Wu, Runpei -- Peluso, Esther -- Metzger, Daniel -- Ichinose, Hiroshi -- Shaked, Iftach -- Chodaczek, Grzegorz -- Biswas, Subhra K -- Hedrick, Catherine C -- F32 HL117533-02/HL/NHLBI NIH HHS/ -- R01 CA202987/CA/NCI NIH HHS/ -- R01 HL118765/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 2015 Nov 20;350(6263):985-90. doi: 10.1126/science.aac9407. Epub 2015 Oct 22.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA. rhanna@lji.org hedrick@lji.org. ; Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey. ; Izmir Biomedicine and Genome Center, Dokuz Eylul University, Izmir, Turkey. ; Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA. ; Microscopy Core, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA. ; Department of Functional Genomics and Cancer, Institut de Genetique et de Biologie Moleculaire et Cellulaire (IGBMC), INSERM U964, CNRS UMR 7104, Universite de Strasbourg, Illkirch, France. ; Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan. ; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/26494174" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Immunologic Surveillance/*immunology ; Immunotherapy/methods ; Killer Cells, Natural/immunology ; Lung Neoplasms/*immunology/*secondary/therapy ; Mice ; Mice, Mutant Strains ; Monocytes/*immunology ; Neoplasm Invasiveness ; Neoplasm Metastasis ; Neoplasms, Experimental/immunology/secondary ; Nuclear Receptor Subfamily 4, Group A, Member 1/genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Rift Basins in Western Margin of India and Their Hydrocarbon Prospects with Special Reference to Kutch Basin (1982)
    American Association of Petroleum Geologists
    Details
    Publication Date: 1982-01-01
    Print ISSN: 0149-1423
    Electronic ISSN: 1943-2674
    Topics: Geosciences
    Published by American Association of Petroleum Geologists
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  • 3
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    Rift Basins in Western Margin of India with Special Reference to Kutch Basin and its Hydrocarbon Prospects: ABSTRACT (1981)
    American Association of Petroleum Geologists
    Details
    Publication Date: 1981-01-01
    Print ISSN: 0149-1423
    Electronic ISSN: 1943-2674
    Topics: Geosciences
    Published by American Association of Petroleum Geologists
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  • 4
    Electronic Resource
    Electronic Resource
    Ultrasound induced lubricity in microscopic contact (1997)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 71 (1997), S. 1177-1179 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A physical effect of ultrasound induced lubricity is reported. We studied the dynamic friction dependence on out-of-plane ultrasonic vibration of a sample using friction force microscopy and a scanning probe technique, the ultrasonic force microscope, which can probe the dynamics of the tip–sample elastic contact at a submicrosecond scale. The results show that friction vanishes when the tip–surface contact breaks for part of the out-of-plane vibration cycle. Moreover, the friction force reduces well before such a break, and this reduction does not depend on the normal load. This suggests the presence on the surface of a layer with viscoelastic behavior. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.120417
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  • 5
    Electronic Resource
    Electronic Resource
    Effect of roughness on the measurement of nanohardness—a computer simulation study (1997)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 71 (1997), S. 1059-1061 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: This letter reports a simulation study of depth sensing nanoindentation on a rough surface. The estimated mean hardness and scatter are both influenced by roughness, irrespective of whether there is a genuine variation in mechanical property with deformation volume/depth. The scatter due to roughness always decreases with penetration depth. The roughness dependency of hardness is the product of two terms. The first term is independent of property variation with deformation volume/depth and arises due to the discrete nature of multiple contacts during indentation. The second term is due to property variation with deformation volume/depth, as changing roughness changes the aggregate strength of each contact island. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.119727
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  • 6
    Electronic Resource
    Electronic Resource
    Mechanical Properties of Rough TiN Coating Deposited on Steel by Cathodic Arc Evaporation Technique (2005)
    Oxford, UK : Blackwell Science Inc
    Journal of the American Ceramic Society 88 (2005), S. 0 
    Details
    ISSN: 1551-2916
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: We investigate here the axial and transverse mechanical properties of thin (1.5–7 μm) titanium nitride films deposited on high-speed steel by cathodic arc evaporation. The deposited films are rough, the roughness varying with film thickness. Mechanical properties deconvoluted from nanoindentation data show variations with penetration depth and scatter. We explore the effect of film surface roughness on these variations and comment on the possible effects of material heterogeneity and crystal structure on the estimated properties.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1551-2916.2005.00328.x
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  • 7
    Electronic Resource
    Electronic Resource
    A PORTABLE PROTON PRECESSION MAGNETOMETER (1966)
    Oxford, UK : Blackwell Publishing Ltd
    Geophysical prospecting 14 (1966), S. 0 
    Details
    ISSN: 1365-2478
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences , Physics
    Notes: The paper describes a transistorised, portable proton precession magnetometer constructed for surface geophysical prospecting. Constructional and circuit details are furnished. The readout of the instrument is digital. The accuracy of measurement is ± 1 part in 20,000. The maximum gradient of the total field under which a satisfactory measurement can be made is about 1 gamma/cm. The sensing head uses a single coil system with distilled water as the proton sample.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2478.1966.tb01762.x
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  • 8
    Electronic Resource
    Electronic Resource
    On forced torsional oscillation of a cylindrical shell of non-homogeneous material by the application of a periodic shearing force at one end (1969)
    Springer
    Pure and applied geophysics 73 (1969), S. 39-42 
    Details
    ISSN: 1420-9136
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Summary In the present note the author has considered the torsional vibration of a cylindrical shell of non-homogeneous material whose rigidity and density vary linearly with distance from the axis of the shell. It is assumed that one end of the shell is fixed while the other end is acted on by a periodic shearing force, both the inner and the outer curved surface being free from stress at all times.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00875119
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  • 9
    Electronic Resource
    Electronic Resource
    Note on the torsional vibration of a thin beam of varying cross-section (1970)
    Springer
    Pure and applied geophysics 79 (1970), S. 18-21 
    Details
    ISSN: 1420-9136
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Summary In the present note the problem of torsional vibration of a bar in which the moment of inertia and the torsional rigidity are proportional to μ0 + μ1s, wheres is the spanwise co-ordinate and μ0 and μ1 are real numbers, has been considered.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00875473
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  • 10
    Electronic Resource
    Electronic Resource
    On the compositional dependence of the optical gap and structural properties of amorphous In x Se1−x thin films (1991)
    Springer
    Journal of materials science 2 (1991), S. 174-176 
    Details
    ISSN: 1573-482X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The optical gap of the amorphous In x Se1−x thin film has been observed to decrease with increasing content of indium in the film (x). An attempt is made to interpret the compositional dependence of the optical gap in amorphous In x Se1−x thin film in an alloy-like approach. It has been found that introduction of higher concentrations of indium imparts greater stability to the structure of the indium selenium alloy. From the study of the radial distribution function (RDF) by X-rays it is observed that there is a correlation between the coordination number and the optical gap of indium selenide thin films.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00696295
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