ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
Collection
Keywords
Publisher
Language
Years
  • 1
    facet.materialart.
    Unknown
    Dispensability of zinc and the putative zinc-binding domain in bacterial glutamyl-tRNA synthetase (2015)
    Portland Press
    Details
    Publication Date: 2015-02-17
    Description: The putative zinc-binding domain ( pZBD ) in Escherichia coli glutamyl-tRNA synthetase (GluRS) is known to correctly position the tRNA acceptor arm and modulate the amino acid binding site. However, its functional role in other bacterial species is not clear since many bacterial GluRSs lack a Zn-binding motif in the pZBD . From experimental studies on pZBD -swapped E. coli GluRS, with Thermosynechoccus elongates GluRS, Burkholderia thailandensis GluRS and E. coli glutamyl-queuosine-tRNA Asp synthetase, we show that E. coli GluRS, containing the Zn-free pZBD of B. thailandensis , is as functional as the Zn-bound wild type E. coli GluRS, while the other constructs, all Zn-bound, show impaired function. A pZBD -tinkered version of E. coli GluRS, that still retained Zn-binding capacity, also showed reduced activity. This suggests that zinc is not essential for the pZBD to be functional. From extensive structural and sequence analyses from whole genome database of bacterial GluRS we further show that in addition to many bacterial GluRS lacking a Zn-binding motif, the pZBD is actually deleted in some bacteria, all containing either glutaminyl-tRNA synthetase or a second copy of GluRS (GluRS2). Correlation between the absence of pZBD and the occurrence of glutamine amidotransferase CAB (GatCAB) in the genome suggests that the primordial role of the pZBD was to facilitate transamidation of misacylated Glu-tRNA Gln via interaction with GatCAB, while its role in tRNA Glu interaction may be a consequence of the presence of pZBD .
    Print ISSN: 0144-8463
    Electronic ISSN: 1573-4935
    Topics: Biology , Chemistry and Pharmacology
    Published by Portland Press
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 2
    facet.materialart.
    Unknown
    PORE PRESSURE MODELLING IN A COMPRESSIONAL SETTING: A CASE STUDY FROM ASSAM, NE INDIA (2019)
    Details
    Publication Date: 2019
    Description: The petroleum‐bearing Assam oil province, NE India, has a complex tectonic history resulting from the Cenozoic collision of the Indian Plate with the Eurasian and Burma Plates. Well data show that there are significant variations in the magnitude and stratigraphic occurrence of overpressures across the foreland basin. In areas which have not been affected by thrust tectonics, analyses of pore pressures in Upper Miocene to Eocene and underlying sequences indicate that overpressures are caused by disequilibrium compaction. Pore pressures were observed to be 25.8–28 MPa over a depth interval of 2259–2382 m and 43–45 MPa between depths of 3820 m and 3994 m. In the adjacent Schuppen (fold‐thrust) belt, multiple overpressure regimes are recognised and disequilibrium compaction is the main cause of the overpressures in both the supra‐thrust and the sub‐thrust successions. Unloading due to uplift and erosion in the supra‐thrust section of the Schuppen belt was quantified using velocity data and the normal compaction trend for shales; net uplift was estimated to total 1000–1600 m with a standard deviation of 250–476 m. Overpressure development in supra‐thrust strata in the Schuppen belt suggests the possible effects of normal burial prior to tectonic deformation, as well as of compaction related to high horizontal stresses resulting from thrusting and associated fold development. Pore pressures in the supra‐thrust section, over a depth interval of 700–1400 m which corresponds to the Oligocene to Upper Miocene succession, were observed to range from 9.6 to 19.5 MPa. The top of the overpressured zone in sub‐thrust strata was observed in the Upper Eocene to Oligocene succession at a depth of 3700 m, in the argillaceous Barail Formation, with pore pressures ranging between 48 MPa and 54 MPa. Pore pressures were estimated using acoustic log data calibrated to measured pressures from Modular Dynamic and Drill Stem Test data. The modelled pore pressures closely correspond to the measured data, supporting the robustness of the model. The numerical parameters defined in this study may be used for future exploration in the region.
    Print ISSN: 0141-6421
    Electronic ISSN: 1747-5457
    Topics: Geosciences
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 3
    facet.materialart.
    Unknown
    Valley degeneracy in biaxially strained aluminum arsenide quantum wells (2011)
    American Physical Society (APS)
    Details
    Publication Date: 2011-09-17
    Description: Author(s): S. Prabhu-Gaunkar, S. Birner, S. Dasgupta, C. Knaak, and M. Grayson This paper describes a complete analytical formalism for calculating electron subband energy and degeneracy in strained multivalley quantum wells grown along any orientation with explicit results for AlAs quantum wells (QWs). In analogy to the spin index, the valley degree of freedom is justified as... [Phys. Rev. B 84, 125319] Published Fri Sep 16, 2011
    Keywords: Semiconductors II: surfaces, interfaces, microstructures, and related topics
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 4
    facet.materialart.
    Unknown
    The Fate of Sulfur During Fluid-Present Melting of Subducting Basaltic Crust at Variable Oxygen Fugacity (2014)
    Oxford University Press
    Details
    Publication Date: 2014-05-31
    Description: To constrain the effect of redox state on sulfur transport from subducting crust to mantle wedge during fluid-present melting and the stability of sulfur-bearing phases in the downgoing ocean crust, here we report high-pressure phase equilibria experiments on a H 2 O-saturated mid-ocean ridge basalt with 1 wt % S at variable oxygen fugacity ( ). Double-capsule experiments were conducted at 2·0 and 3·0 GPa and 950–1050°C, using Co–CoO, Ni–NiO, Ni x Pd 1– x –NiO, and Fe 2 O 3 –Fe 3 O 4 external buffers. Sulfur content at sulfide saturation (SCSS) or sulfur content at sulfate saturation (SCAS) of experimental hydrous partial melts was measured by electron microprobe. All experiments were fluid-saturated and produced either pyrrhotite- or anhydrite-saturated assemblages of silicate glass, clinopyroxene, garnet, and rutile or titanomagnetite, ± amphibole ± quartz ± orthopyroxene. The silicate partial melt composition evolves from rhyolitic at 950°C to trachydacitic and trachyandesitic at 1050°C with increasing . At pyrrhotite saturation, melt S contents range from ~30 ppm S at 〈 FMQ – 1 to ~500 ppm S at FMQ 〈 ≤ FMQ + 1·1, whereas at anhydrite saturation ( ≥ FMQ + 2·5) melt S concentrations range from ~700 ppm S to 0·3 wt % S. Mass-balance calculations suggest that the aqueous fluid phase at equilibrium may contain as much as ~15 wt % S at 1050°C at pyrrhotite saturation ( ≤ FMQ + 1·1), in agreement with previous estimates, and up to 8 wt % S at anhydrite saturation. Our data also show that decreases markedly with increasing at pyrrhotite saturation, from several thousand at 〈 FMQ – 1 to ~ 200–400 at FMQ 〈 ≤ FMQ + 1·1, owing to the increase of melt S content. At anhydrite saturation, is very low (〈100) but increases with decreasing temperature, in an opposite way to previous observations at pyrrhotite saturation. As a consequence, at T ≤ 900°C, might be in the range 200 ± 100, irrespective of . The present study confirms that slab partial melts saturated with pyrrhotite are unable to efficiently transport S from slab to mantle wedge, and suggests that slab partial melts in equilibrium with anhydrite also have very limited power to enrich the mantle wedge in S. Importantly, slab-derived aqueous fluids appear to be efficient vectors for the transport of sulfur from slab to mantle wedge at all . Therefore, S transfer from ocean crust to wedge mantle is not dependent and could take place over a range of conditions, and oxidized slab conditions are not necessarily required to enrich the mantle wedge in S. Finally, depending on the initial amount of sulfur in the slab, the proportion of residual anhydrite and pyrrhotite in the dehydrated slab below the region of formation of arc magmas is likely to be significant and may efficiently be recycled into the deep mantle.
    Print ISSN: 0022-3530
    Electronic ISSN: 1460-2415
    Topics: Geosciences
    Published by Oxford University Press
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 5
    facet.materialart.
    Unknown
    Constraining the conditions of Barrovian metamorphism in Sikkim, India: P-T-t paths of garnet crystallization in the Lesser Himalayan Belt (2014)
    Wiley
    Details
    Publication Date: 2014-09-25
    Description: Garnet crystallization in metapelites from the Barrovian garnet and staurolite zones of the Lesser Himalayan Belt in Sikkim is modelled utilizing Gibbs free energy minimization, multi-component diffusion theory, and a simple nucleation and growth algorithm. The predicted mineral assemblages and garnet growth zoning match observations remarkably well for relatively tight, clockwise meta morphic pressure{temperature paths that are characterized by prograde gradients of ~30°C/kbar for garnet-zone rocks and ~20°C/kbar for rocks from the staurolite zone. Estimates for peak metamorphic temperature increase up-structure toward the Main Central Thrust. According to our calculations, garnet stopped growing at peak pressures, and protracted heating after peak pressure was absent or insignificant. Almost identical pressure{temperature paths for the samples studied and the metamorphic continuity of the Lesser Himalayan Belt support thermo-mechanical models that favour tectonic inversion of a coherent package of Barrovian metamorphic rocks. Timescales associated with the metamorphism were too short for chemical diffusion to substantially modify garnet growth zoning in rocks from the garnet and staurolite zones. In general, the pressure of initial garnet growth decreases, and the temperature required for initial garnet growth was reached earlier, for rocks buried closer toward the MCT. Deviations from this overall trend can be explained by variations in bulk rock chemistry. This article is protected by copyright. All rights reserved.
    Print ISSN: 0263-4929
    Electronic ISSN: 1525-1314
    Topics: Geosciences
    Published by Wiley
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 6
    facet.materialart.
    Unknown
    Expanded view of universities would be more realistic (2010)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2010-02-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dasgupta, Siddharth -- England -- Nature. 2010 Feb 4;463(7281):608. doi: 10.1038/463608c.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20130631" target="_blank"〉PubMed〈/a〉
    Keywords: Curriculum/trends ; Education, Distance/trends ; International Cooperation ; Universities/*trends
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 7
    facet.materialart.
    Unknown
    Benzene forms hydrogen bonds with water (1992)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1992-08-14
    Description: Fully rotationally resolved spectra of three isotopic species of 1:1 clusters of benzene with water (H(2)O, D(2)O, and HDO) were fit to yield moments of inertia that demonstrate unambiguously that water is positioned above the benzene plane in nearly free internal rotation with both hydrogen atoms pointing toward the pi cloud. Ab initio calculations (MP2 level of electron correlation and 6-31 G(**) basis set with basis set superposition error corrections) predict a binding energy D(e) greater, similar 1.78 kilocalories per mole. In both the experimental and theoretical structures, water is situated nearly 1 angstrom within the van der Waals contacts of the monomers, a clear manifestation of hydrogen bond formation in this simple model of aqueous-pi electron interactions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Suzuki, S -- Green, P G -- Bumgarner, R E -- Dasgupta, S -- Goddard, W A 3rd -- Blake, G A -- New York, N.Y. -- Science. 1992 Aug 14;257(5072):942-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17789637" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 8
    facet.materialart.
    Unknown
    Transposition-driven genomic heterogeneity in the Drosophila brain (2013)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2013-04-06
    Description: Recent studies in mammals have documented the neural expression and mobility of retrotransposons and have suggested that neural genomes are diverse mosaics. We found that transposition occurs among memory-relevant neurons in the Drosophila brain. Cell type-specific gene expression profiling revealed that transposon expression is more abundant in mushroom body (MB) alphabeta neurons than in neighboring MB neurons. The Piwi-interacting RNA (piRNA) proteins Aubergine and Argonaute 3, known to suppress transposons in the fly germline, are expressed in the brain and appear less abundant in alphabeta MB neurons. Loss of piRNA proteins correlates with elevated transposon expression in the brain. Paired-end deep sequencing identified more than 200 de novo transposon insertions in alphabeta neurons, including insertions into memory-relevant loci. Our observations indicate that genomic heterogeneity is a conserved feature of the brain.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887341/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887341/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Perrat, Paola N -- DasGupta, Shamik -- Wang, Jie -- Theurkauf, William -- Weng, Zhiping -- Rosbash, Michael -- Waddell, Scott -- 090309/Wellcome Trust/United Kingdom -- 090924/Wellcome Trust/United Kingdom -- MH069883/MH/NIMH NIH HHS/ -- MH081982/MH/NIMH NIH HHS/ -- NS044232/NS/NINDS NIH HHS/ -- NS045713/NS/NINDS NIH HHS/ -- P01 NS044232/NS/NINDS NIH HHS/ -- P30 NS045713/NS/NINDS NIH HHS/ -- R01 HD049116/HD/NICHD NIH HHS/ -- R01 MH069883/MH/NIMH NIH HHS/ -- R01 MH081982/MH/NIMH NIH HHS/ -- R01HD049116/HD/NICHD NIH HHS/ -- Howard Hughes Medical Institute/ -- Wellcome Trust/United Kingdom -- New York, N.Y. -- Science. 2013 Apr 5;340(6128):91-5. doi: 10.1126/science.1231965.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Neurobiology, University of Massachusetts Medical School, Worcester, MA 01605, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23559253" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Argonaute Proteins/metabolism ; Brain/cytology/*metabolism ; Drosophila Proteins/metabolism ; Drosophila melanogaster/*genetics ; *Gene Expression Regulation ; Genome, Insect/*genetics ; Mushroom Bodies/cytology/metabolism ; Neurons/metabolism ; Peptide Initiation Factors/metabolism ; RNA, Small Interfering/metabolism ; Retroelements/*genetics ; Transcriptome
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 9
    facet.materialart.
    Unknown
    FoxP influences the speed and accuracy of a perceptual decision in Drosophila (2014)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2014-05-24
    Description: Decisions take time if information gradually accumulates to a response threshold, but the neural mechanisms of integration and thresholding are unknown. We characterized a decision process in Drosophila that bears the behavioral signature of evidence accumulation. As stimulus contrast in trained odor discriminations decreased, reaction times increased and perceptual accuracy declined, in quantitative agreement with a drift-diffusion model. FoxP mutants took longer than wild-type flies to form decisions of similar or reduced accuracy, especially in difficult, low-contrast tasks. RNA interference with FoxP expression in alphabeta core Kenyon cells, or the overexpression of a potassium conductance in these neurons, recapitulated the FoxP mutant phenotype. A mushroom body subdomain whose development or function require the transcription factor FoxP thus supports the progression of a decision toward commitment.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206523/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206523/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉DasGupta, Shamik -- Ferreira, Clara Howcroft -- Miesenbock, Gero -- 090309/Wellcome Trust/United Kingdom -- G0700888/Medical Research Council/United Kingdom -- G0701225/Medical Research Council/United Kingdom -- R01 DA030601/DA/NIDA NIH HHS/ -- Wellcome Trust/United Kingdom -- New York, N.Y. -- Science. 2014 May 23;344(6186):901-4. doi: 10.1126/science.1252114.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Centre for Neural Circuits and Behaviour, University of Oxford, Tinsley Building, Mansfield Road, Oxford, OX1 3SR, UK. ; Centre for Neural Circuits and Behaviour, University of Oxford, Tinsley Building, Mansfield Road, Oxford, OX1 3SR, UK. gero.miesenboeck@cncb.ox.ac.uk.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24855268" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Behavior, Animal ; Cell Line ; *Decision Making ; Drosophila Proteins/genetics/*physiology ; Drosophila melanogaster/genetics/*physiology ; Forkhead Transcription Factors/genetics/*physiology ; Mushroom Bodies/growth & development/metabolism ; Mutation ; Neurons/physiology ; Odors ; *Psychomotor Performance ; RNA Interference ; Reaction Time/genetics/*physiology ; Smell
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 10
    facet.materialart.
    Unknown
    Delivery of carbon, nitrogen, and sulfur to the silicate Earth by a giant impact (2019)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2019
    Description: 〈p〉Earth’s status as the only life-sustaining planet is a result of the timing and delivery mechanism of carbon (C), nitrogen (N), sulfur (S), and hydrogen (H). On the basis of their isotopic signatures, terrestrial volatiles are thought to have derived from carbonaceous chondrites, while the isotopic compositions of nonvolatile major and trace elements suggest that enstatite chondrite–like materials are the primary building blocks of Earth. However, the C/N ratio of the bulk silicate Earth (BSE) is superchondritic, which rules out volatile delivery by a chondritic late veneer. In addition, if delivered during the main phase of Earth’s accretion, then, owing to the greater siderophile (metal loving) nature of C relative to N, core formation should have left behind a subchondritic C/N ratio in the BSE. Here, we present high pressure-temperature experiments to constrain the fate of mixed C-N-S volatiles during core-mantle segregation in the planetary embryo magma oceans and show that C becomes much less siderophile in N-bearing and S-rich alloys, while the siderophile character of N remains largely unaffected in the presence of S. Using the new data and inverse Monte Carlo simulations, we show that the impact of a Mars-sized planet, having minimal contributions from carbonaceous chondrite-like material and coinciding with the Moon-forming event, can be the source of major volatiles in the BSE.〈/p〉
    Electronic ISSN: 2375-2548
    Topics: Natural Sciences in General
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...