ISSN:
1420-9071
Keywords:
Canine heart
;
electron paramagnetic resonance
;
local ischemia
;
microdialysis
;
oxygen radicals
;
spintrapping
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract A new experimental approach for spin-trapping of oxygen radicals in a selected region of the heart in situ is described. This approach is based on microdialysis, and it permits the detection of oxygen radicals in conditions of local ischemia and restoration of normal blood flow. Increased hydroxyl radical generation in an ischemic area of canine myocardium, as a result of 40 min local occlusion, has been studied.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01952872
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