Electronic Resource
New York, NY
:
Wiley-Blackwell
International Journal of Quantum Chemistry
9 (1975), S. 473-478
ISSN:
0020-7608
Keywords:
Computational Chemistry and Molecular Modeling
;
Atomic, Molecular and Optical Physics
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A theory of UV carcinogenesis is described in which damage to DNA in the form of pyrimidine dimers occurs in a critical operator region of the genome that controls the synthesis of divisional proteins. There is a chance that a mutation will occur in the region of the operator either during replication or during postreplication repair, so that unchecked growth will be passed on to daughter cells. Comparison with the experiments of Hart and Setlow (1973) indicates that agreement is semiquantitative.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/qua.560090309
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