ISSN:
1435-604X
Keywords:
Photosensitization
;
Singlet oxygen
;
Porphyrins
;
Phorbides
;
Purpurins
;
Phthalocyanines
;
Naphthalocyanines
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
,
Physics
,
Technology
Notes:
Abstract Tetrapyrroles obtain very good photophysical properties to be potent photosensitizers. They have long triplet lifetimes and high quantum yields. The singlet oxygen quantum yields are high too, because of the low energy gap between the triplet states of the most tetrapyrroles and molecular oxygen. A large variety of tetrapyrroles with different absorbance in the red and near infrared region of the spectrum and different hydrophobic properties (which are not discussed in this paper) are synthetisized and tested. A lot of them were shown to be effective sensitizers in vivo. Because of their photophysical properties, their selective accumulation and their relative biological harmfulness it could be proposed that some of these sensitizers may become important for clinical PDT.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02031370
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