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  • 1
    Publication Date: 1995-09-01
    Print ISSN: 0167-2789
    Electronic ISSN: 1872-8022
    Topics: Physics
    Published by Elsevier
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  • 2
    ISSN: 1435-604X
    Keywords: Keywords: Diffuser; Emission profile; Fluorescence imaging; Interstitial laser photocoagulation; Photodynamic therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract . Cylindrical light diffusers are commercially available for clinical applications such as photodynamic therapy (PDT) and interstitial laser photocoagulation (ILP). A fluorescence imaging technique has been used to quantify the light distribution produced by each of six different diffuser fibres. The light distribution produced by each device was found to depend on the distance the light propagated in the fluorescent dye solution. At a distance of 1 mm from the diffuser midline, the measured profiles were found to be consistent with published results obtained in air at a similar distance. The three devices intended for PDT utilised scattering particles and reflectors in their construction. The profiles produced by these applicators revealed peaks that were attributed to the reflectors located at their distal tips. By comparison, the two etched ILP fibres displayed either a strong modulation in the profile due to non-uniform etching or a predominant forward peak associated with the conical shape of the tip. We conclude that it is important to take into account the forward-directed light emitted by the diffusers when considering clinical applications using these devices.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Lasers in medical science 14 (1999), S. 67-72 
    ISSN: 1435-604X
    Keywords: Keywords: Emission profile; ILP; Light diffuser; PDT; Tissue phantom; Video camera
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract. The uniformity of the emission profile produced by a cylindrical light diffuser is an important parameter for determining the light dose received by the target tissue during laser therapies such as photodynamic therapy (PDT) and interstitial laser photocoagulation (ILP). A technique originally used for determining the profile of a laser beam with a commercial video camera is adapted in order to measure the distribution of light from a cylindrical diffuser. The method can produce quantitative one-dimensional beam profiles in both the circumferential and axial direction of the light diffuser. The system allows the use of tissue phantoms that provide a convenient and effective method for comparing manufacturer's measurements often made in air with those to be expected in vivo. The technique is a quick and easy method for assessing light diffusers before treatment, and utilises readily available equipment that does not require specialist knowledge. Also, the response of the video camera facilitates the assessment of diffusers over a relatively broad optical spectrum, which encompasses the range of wavelengths currently used for both PDT (515–675 nm) and ILP (800–1064 nm).
    Type of Medium: Electronic Resource
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