Publication Date:
2013-02-19
Description:
A stereoselective total synthesis of multiplolide A ( 1 ) and of its diastereoisomer 2 was described from easily accessible starting materials ( Schemes 2 – 4 ). The synthetic strategy involves a Jacobsen resolution, Sharpless epoxidation, Swern oxidation, Yamaguchi reaction, and ring-closing metathesis (RCM).
Print ISSN:
0018-019X
Electronic ISSN:
1522-2675
Topics:
Chemistry and Pharmacology
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