Publication Date:
2015-05-09
Description:
Article The NFκB signalling pathway is regulated through the formation of transcription factor dimers but mechanisms controlling their formation are poorly understood. Here, Tsui et al . report that IκBb is a positive regulator of Rel-NFκB dimer formation, using in vitro and in vivo experiments and mathematical modelling. Nature Communications doi: 10.1038/ncomms8068 Authors: Rachel Tsui, Jeffrey D. Kearns, Candace Lynch, Don Vu, Kim A. Ngo, Soumen Basak, Gourisankar Ghosh, Alexander Hoffmann
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
Permalink