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  • 1
    Monograph available for loan
    Monograph available for loan
    Redlands, Calif. : ESRI Press
    Call number: 8/M 03.0226
    Type of Medium: Monograph available for loan
    Pages: xiv, 140 S.
    ISBN: 1589480406
    Classification:
    B..
    Location: Upper compact magazine
    Branch Library: GFZ Library
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  • 2
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    ESRI Press, 160 pp.
    In:  Dordrecht, 616 pp., ESRI Press, 160 pp., vol. 4, no. Subvol. b, pp. 220, (ISBN: 1589480406)
    Publication Date: 2002
    Description: Geographic information system (GIS) technology is a practical tool that every community can use to plan for, respond to, and recover from major disasters, whether they are natural events such as hurricanes or human-caused incidents such as terrorist attacks. By giving responders and disaster managers a way to visually analyze each stage of a disaster and synthesize complex information sets, GIS permits swifter decision-making and clearer communication. Confronting Catastrophe guides readers through five stages of hazards management - identification and planning, mitigation, preparedness, response, and recovery - and demonstrates how GIS can be incorporated into each.
    Keywords: Earthquake risk ; disaster ; management ; mitigation ; e-Government ; decision ; making
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  • 3
    Publication Date: 1997-05-23
    Description: Both subjective and electroencephalographic arousal diminish as a function of the duration of prior wakefulness. Data reported here suggest that the major criteria for a neural sleep factor mediating the somnogenic effects of prolonged wakefulness are satisfied by adenosine, a neuromodulator whose extracellular concentration increases with brain metabolism and which, in vitro, inhibits basal forebrain cholinergic neurons. In vivo microdialysis measurements in freely behaving cats showed that adenosine extracellular concentrations in the basal forebrain cholinergic region increased during spontaneous wakefulness as contrasted with slow wave sleep; exhibited progressive increases during sustained, prolonged wakefulness; and declined slowly during recovery sleep. Furthermore, the sleep-wakefulness profile occurring after prolonged wakefulness was mimicked by increased extracellular adenosine induced by microdialysis perfusion of an adenosine transport inhibitor in the cholinergic basal forebrain but not by perfusion in a control noncholinergic region.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599777/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599777/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Porkka-Heiskanen, T -- Strecker, R E -- Thakkar, M -- Bjorkum, A A -- Greene, R W -- McCarley, R W -- R01 MH039683/MH/NIMH NIH HHS/ -- R37 MH39,683/MH/NIMH NIH HHS/ -- New York, N.Y. -- Science. 1997 May 23;276(5316):1265-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Psychiatry, Harvard Medical School, Brockton Veterans Administration Medical Center (VAMC), 116 A, 940 Belmont Street, Brockton, MA 02401, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9157887" target="_blank"〉PubMed〈/a〉
    Keywords: Adenosine/antagonists & inhibitors/*physiology ; Animals ; Cats ; Electrophysiology ; Microdialysis ; Prosencephalon/physiology ; Sleep/*physiology ; Sleep Deprivation ; Thioinosine/analogs & derivatives/pharmacology ; Time Factors ; Wakefulness/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    Publication Date: 1994-10-14
    Description: Mice deficient for the gene encoding alpha-calcium-calmodulin-dependent kinase II (alpha-CaMKII knockout mice) provide a promising tool to link behavioral and cellular abnormalities with a specific molecular lesion. The heterozygous mouse exhibited a well-circumscribed syndrome of behavioral abnormalities, consisting primarily of a decreased fear response and an increase in defensive aggression, in the absence of any measured cognitive deficits. Unlike the heterozygote, the homozygote displayed abnormal behavior in all paradigms tested. At the cellular level, both extracellular and whole-cell patch clamp recordings indicated that serotonin release in putative serotonergic neurons of the dorsal raphe was reduced. Thus, alpha-CaMKII knockout mice, in particular the heterozygote, may provide a model for studying the molecular and cellular basis underlying emotional disorders involving fear and aggression.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chen, C -- Rainnie, D G -- Greene, R W -- Tonegawa, S -- New York, N.Y. -- Science. 1994 Oct 14;266(5183):291-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Howard Hughes Medical Institute, Center for Cancer Research, Cambridge, MA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7939668" target="_blank"〉PubMed〈/a〉
    Keywords: *Aggression ; Animals ; Behavior, Animal ; Calcium-Calmodulin-Dependent Protein Kinase Type 2 ; Calcium-Calmodulin-Dependent Protein Kinases/deficiency/genetics/*physiology ; *Fear ; Fluoxetine/pharmacology ; Gene Dosage ; Heterozygote ; Homozygote ; In Vitro Techniques ; Membrane Potentials ; Mice ; Mice, Knockout ; Mutation ; Neurons/metabolism ; Patch-Clamp Techniques ; Raphe Nuclei/metabolism ; Serotonin/metabolism/pharmacology ; Synaptic Transmission/drug effects
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
    Publication Date: 1994-02-04
    Description: Increased discharge activity of mesopontine cholinergic neurons participates in the production of electroencephalographic (EEG) arousal; such arousal diminishes as a function of the duration of prior wakefulness or of brain hyperthermia. Whole-cell and extracellular recordings in a brainstem slice show that mesopontine cholinergic neurons are under the tonic inhibitory control of endogenous adenosine, a neuromodulator released during brain metabolism. This inhibitory tone is mediated postsynaptically by an inwardly rectifying potassium conductance and by an inhibition of the hyperpolarization-activated current. These data provide a coupling mechanism linking neuronal control of EEG arousal with the effects of prior wakefulness, brain hyperthermia, and the use of the adenosine receptor blockers caffeine and theophylline.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612520/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612520/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rainnie, D G -- Grunze, H C -- McCarley, R W -- Greene, R W -- R01 MH039683/MH/NIMH NIH HHS/ -- New York, N.Y. -- Science. 1994 Feb 4;263(5147):689-92.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Psychiatry, Harvard University, Brockton, MA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8303279" target="_blank"〉PubMed〈/a〉
    Keywords: Adenosine/*physiology ; Animals ; Arousal/*physiology ; Calcium/metabolism ; Electric Conductivity ; *Electroencephalography/drug effects ; Female ; Frontal Lobe/physiology ; In Vitro Techniques ; Male ; Membrane Potentials ; Neurons/*physiology ; Parasympathetic Nervous System/*physiology ; Potassium/metabolism ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
    Publication Date: 1986-11-07
    Description: Intracellular electrical recordings in an in vitro slice preparation of the brainstem medial pontine reticular formation, a region thought to be important in mediation of desynchronized sleep phenomena, demonstrate a population of neurons that have a calcium-dependent, low threshold spike. This low threshold spike was inactivated at relatively depolarized membrane potential levels and, when this spike was deinactivated, it induced a burst of action potentials. The membrane potential dependence of the spike may underlie changes in action potential firing patterns associated with behavioral state change because the baseline membrane potential in neurons of the medial pontine reticular population depolarizes during passage from waking and slow wave sleep to desynchronized sleep, which is characterized by the absence of burst firing.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Greene, R W -- Haas, H L -- McCarley, R W -- MH 39,683/MH/NIMH NIH HHS/ -- New York, N.Y. -- Science. 1986 Nov 7;234(4777):738-40.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3775364" target="_blank"〉PubMed〈/a〉
    Keywords: Action Potentials ; Animals ; Calcium/physiology ; Electric Stimulation ; In Vitro Techniques ; Membrane Potentials ; Pons/cytology/*physiology ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Environmental geology 22 (1993), S. 321-325 
    ISSN: 1432-0495
    Keywords: Roadway design ; Karst ; Carbonate rocks
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract To minimize costs in conventional roadway design, as much low or valley areas as possible are utilized. In many areas of the eastern United States, these valleys are filled with carbonate rocks. Excavation is used to minimize grades—this removes protective overburden or rock cover over cavities; fill also is used to minimize grades—this can increase loads on marginally stable soil arches or rock cavity roofs. Surface water runoff is directed toward low areas—the low areas are likely zones of weakness or solutioning, thereby increasing the potential for sinkhole development and providing an opportunity for ground—water contamination, and remediation usually consists of blindly filling rock cavities, thus either channeling the still-contaminated surface flows someplace else or perhaps eliminating useful ground water recharge conduits. The authors suggest that the key to proper design, construction, and remediation for roadways planned in karst is to understand the geologic and hydrogeologic setting of the route(s) or locale, perform true geotechnical engineering design, and remediate with an understanding of the overall engineering geologic, hydrogeologic, and environmental picture.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Marine biology 14 (1972), S. 253-259 
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Alcohol-soluble photosynthetic products of chloroplasts symbiotic in three species of sacoglossan slugs (Elysia hedgpethi, Placida dendritica Placobranchus ianthobapsus) were analyzed and compared to products of chloroplasts in an intact alga. Animal-cell chloroplasts appear to lack the ability to synthesize either lipids or sucrose. They do, however, produce greater percentages of TCA-cycle intermediates than do chloroplasts from the intact alga investigated.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Marine biology 7 (1970), S. 138-142 
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract It has been previously reported that many species of the order Sacoglossa (Mollusca: Opisthobranchia) contain algal chloroplasts within the cells of their digestive gland and maintain them in a symbiotic condition. In the present study, two species, Elysia hedgpethi Marcus and Placobranchus ianthobapsus Gould, were compared as to their abilities to retain functional chloroplasts in their tissues. Animals were starved for varying lengths of time, and the functional capacity of the plastids was ascertained at intervals. The chlorophyll content of whole animals, and the ability to incorporate 14CO2 were used as the assay for functional capacity. E. hedgpethi decreased in chlorophyll content during starvation until the tenth day, when no chlorophyll was detectable spectrophoto-metrically. Incorporation of 14CO2 paralleled the decline in chlorophyll, and was at control levels by the tenth day. P. ianthobapsus showed no decline in chlorophyll content over 27 days starvation, although the ability to incorporate 14CO2 showed a decrease.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular neurobiology 5 (1985), S. 297-301 
    ISSN: 1573-6830
    Keywords: long-term potentiation ; 4-aminopyridine ; hippocampal slice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary 1. Long-term potentiation (LTP) of excitatory postsynaptic potentials (epsp's) was investigated with extracellular field potential recording in hippocampal slices from rats. 2. In the presence of 100µM 4-aminopyridine (4-AP) the probability of eliciting LTP was unchanged or increased; the extent of potentiation was not significantly different from normal. 3. During LTP saturation, 4-AP further enhanced the epsp. 4. These data are inconsistent with an involvement of A-current reduction in LTP.
    Type of Medium: Electronic Resource
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