Publication Date:
1979-03-16
Description:
Spleen cells from mice immunized with a cultured human neuroblastoma were hybridized with the mouse plasmacytoma P3X63Ag8. Hybrid myelomas were screened for production of antibodies that reacted with human neuroblastomas but not with cells from other tissues. One of these hybridoma antibodies reacted with an antigen present on the six human neuroblastomas tested, one of two retinoblastomas, a glioblastoma, and fetal brain, but did not react with other tumors or tissues including adult human brain.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kennett, R H -- Gilbert, F -- New York, N.Y. -- Science. 1979 Mar 16;203(4385):1120-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/424740" target="_blank"〉PubMed〈/a〉
Keywords:
*Antigens, Neoplasm/analysis
;
Brain/embryology/*immunology
;
Cell Differentiation
;
Glioma/immunology
;
Humans
;
Hybrid Cells/immunology
;
Myeloma Proteins/immunology
;
Neuroblastoma/*immunology
;
Retinoblastoma/*immunology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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