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  • 1
    Publication Date: 2014-05-14
    Description: Earth-scale planets in the classical habitable zone (HZ) are more likely to be habitable if they possess active geophysics. Without a constant internal energy source, planets cool as they age, eventually terminating tectonic activity. Planets orbiting low-mass stars can be very old, due to the longevity of such stars, so they may be rendered sterile to life in this way. However, the presence of an outer companion could generate enough tidal heat in the HZ planet to prevent such cooling. The range of mass and orbital parameters for the companion that give adequate long-term heating of the inner HZ planet, while avoiding very early total desiccation, is probably substantial. We locate the ideal location for the outer of a pair of planets, under the assumption that the inner planet has the same incident flux as Earth, orbiting example stars: a generic late M dwarf ( T eff  = 2670 K) and the M9V/L0 dwarf DEN1048. Thus discoveries of Earth-scale planets in the HZ zone of old small stars should be followed by searches for outer companion planets that might be essential for current habitability.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
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  • 2
    Publication Date: 2015-04-08
    Description: Reference collections of multiple Drosophila lines with accumulating collections of "omics" data have proven especially valuable for the study of population genetics and complex trait genetics. Here we present a description of a resource collection of 84 strains of Drosophila melanogaster whose genome sequences were obtained after 12 generations of full-sib inbreeding. The initial rationale for this resource was to foster development of a systems biology platform for modeling metabolic regulation by the use of natural polymorphisms as perturbations. As reference lines, they are amenable to repeated phenotypic measurements, and already a large collection of metabolic traits have been assayed. Another key feature of these strains is their widespread geographic origin, coming from Beijing, Ithaca, Netherlands, Tasmania, and Zimbabwe. After obtaining 12.5 x coverage of paired-end Illumina sequence reads, SNP and indel calls were made with the GATK platform. Thorough quality control was enabled by deep sequencing one line to 〉100 x , and single-nucleotide polymorphisms and indels were validated using ddRAD-sequencing as an orthogonal platform. In addition, a series of preliminary population genetic tests were performed with these single-nucleotide polymorphism data for assessment of data quality. We found 83 segregating inversions among the lines, and as expected these were especially abundant in the African sample. We anticipate that this will make a useful addition to the set of reference D. melanogaster strains, thanks to its geographic structuring and unusually high level of genetic diversity.
    Electronic ISSN: 2160-1836
    Topics: Biology
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  • 3
    Publication Date: 2012-03-14
    Description: Wnts make up a large family of extracellular signaling molecules that play crucial roles in development and disease. A subset of noncanonical Wnts signal independently of the transcription factor β-catenin by a mechanism that regulates key morphogenetic movements during embryogenesis. The best characterized noncanonical Wnt, Wnt5a, has been suggested to signal via a variety of different receptors, including the Ror family of receptor tyrosine kinases, the Ryk receptor tyrosine kinase, and the Frizzled seven-transmembrane receptors. Whether one or several of these receptors mediates the effects of Wnt5a in vivo is not known. Through loss-of-function experiments in mice, we provide conclusive evidence that Ror receptors mediate Wnt5a-dependent processes in vivo and identify Dishevelled phosphorylation as a physiological target of Wnt5a–Ror signaling. The absence of Ror signaling leads to defects that mirror phenotypes observed in Wnt5a null mutant mice, including decreased branching of sympathetic neuron axons and major defects in aspects of embryonic development that are dependent upon morphogenetic movements, such as severe truncation of the caudal axis, the limbs, and facial structures. These findings suggest that Wnt5a–Ror–Dishevelled signaling constitutes a core noncanonical Wnt pathway that is conserved through evolution and is crucial during embryonic development.
    Keywords: Inaugural Articles
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 4
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-09-18
    Description: Cycloidal patterns are widely distributed on the surface of Jupiter's moon Europa. Tensile cracks may have developed such a pattern in response to diurnal variations in tidal stress in Europa's outer ice shell. When the tensile strength of the ice is reached, a crack may occur. Propagating cracks would move across an ever-changing stress field, following a curving path to a place and time where the tensile stress was insufficient to continue the propagation. A few hours later, when the stress at the end of the crack again exceeded the strength, propagation would continue in a new direction. Thus, one arcuate segment of the cycloidal chain would be produced during each day on Europa. For this model to work, the tensile strength of Europa's ice crust must be less than 40 kilopascals, and there must be a thick fluid layer below the ice to allow sufficient tidal amplitude.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hoppa, G V -- Tufts, B R -- Greenberg, R -- Geissler, P E -- New York, N.Y. -- Science. 1999 Sep 17;285(5435):1899-902.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Lunar and Planetary Laboratory, 1629 East University Boulevard, University of Arizona, Tucson, AZ 85721-0092, USA. hoppa@lpl.arizona.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10489365" target="_blank"〉PubMed〈/a〉
    Keywords: Extraterrestrial Environment ; Ice ; *Jupiter
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
    Publication Date: 1992-09-18
    Description: Galileo images of Gaspra reveal it to be an irregularly shaped object (19 by 12 by 11 kilometers) that appears to have been created by a catastrophic collisional disruption of a precursor parent body. The cratering age of the surface is about 200 million years. Subtle albedo and color variations appear to correlate with morphological features: Brighter materials are associated with craters especially along the crests of ridges, have a stronger 1-micrometer absorption, and may represent freshly excavated mafic materials; darker materials exhibiting a significantly weaker 1-micrometer absorption appear concentrated in interridge areas. One explanation of these patterns is that Gaspra is covered with a thin regolith and that some of this material has migrated downslope in some areas.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Belton, M J -- Veverka, J -- Thomas, P -- Helfenstein, P -- Simonelli, D -- Chapman, C -- Davies, M E -- Greeley, R -- Greenberg, R -- Head, J -- Murchie, S -- Klaasen, K -- Johnson, T V -- McEwen, A -- Morrison, D -- Neukum, G -- Fanale, F -- Anger, C -- Carr, M -- Pilcher, C -- New York, N.Y. -- Science. 1992 Sep 18;257(5077):1647-52.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17841160" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
    Publication Date: 1991-09-27
    Description: Images of Venus taken at 418 (violet) and 986 [near-infrared (NIR)] nanometers show that the morphology and motions of large-scale features change with depth in the cloud deck. Poleward meridional velocities, seen in both spectral regions, are much reduced in the NIR In the south polar region the markings in the two wavelength bands are strongly anticorrelated. The images follow the changing state of the upper cloud layer downwind of the subsolar point, and the zonal flow field shows a longitudinal periodicity that may be coupled to the formation of large-scale planetary waves. No optical lightning was detected.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Belton, M J -- Gierasch, P J -- Smith, M D -- Helfenstein, P -- Schinder, P J -- Pollack, J B -- Rages, K A -- Ingersoll, A P -- Klaasen, K P -- Veverka, J -- Anger, C D -- Carr, M H -- Chapman, C R -- Davies, M E -- Fanale, F P -- Greeley, R -- Greenberg, R -- Head, J W 3rd -- Morrison, D -- Neukum, G -- Pilcher, C B -- New York, N.Y. -- Science. 1991 Sep 27;253(5027):1531-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17784096" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1991-10-04
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Greenberg, B R -- New York, N.Y. -- Science. 1991 Oct 4;254(5028):11.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1925550" target="_blank"〉PubMed〈/a〉
    Keywords: *Patents as Topic ; *Peer Review
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
    Publication Date: 1992-01-31
    Description: Multispectral images of the lunar western limb and far side obtained from Galileo reveal the compositional nature of several prominent lunar features and provide new information on lunar evolution. The data reveal that the ejecta from the Orientale impact basin (900 kilometers in diameter) lying outside the Cordillera Mountains was excavated from the crust, not the mantle, and covers pre-Orientale terrain that consisted of both highland materials and relatively large expanses of ancient mare basalts. The inside of the far side South Pole-Aitken basin (〉2000 kilometers in diameter) has low albedo, red color, and a relatively high abundance of iron- and magnesium-rich materials. These features suggest that the impact may have penetrated into the deep crust or lunar mantle or that the basin contains ancient mare basalts that were later covered by highlands ejecta.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Belton, M J -- Head, J W 3rd -- Pieters, C M -- Greeley, R -- McEwen, A S -- Neukum, G -- Klaasen, K P -- Anger, C D -- Carr, M H -- Chapman, C R -- Davies, M E -- Fanale, F P -- Gierasch, P J -- Greenberg, R -- Ingersoll, A P -- Johnson, T -- Paczkowski, B -- Pilcher, C B -- Veverka, J -- New York, N.Y. -- Science. 1992 Jan 31;255(5044):570-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17792379" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
    Publication Date: 2004-01-31
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dietsch, Thomas V -- Philpott, Stacy M -- Rice, Robert A -- Greenberg, Russell -- Bichier, Peter -- New York, N.Y. -- Science. 2004 Jan 30;303(5658):625-6; author reply 625-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/14752143" target="_blank"〉PubMed〈/a〉
    Keywords: Agriculture ; Animals ; Coffea/*growth & development ; *Coffee/economics ; Commerce ; *Conservation of Natural Resources ; *Crops, Agricultural/economics ; *Ecosystem ; *Public Policy ; Trees ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
    Publication Date: 2004-11-30
    Description: High-resolution images of the surface of asteroid 433 Eros revealed evidence of downslope movement of a loose regolith layer, as well as the degradation and erasure of small impact craters (less than approximately 100 meters in diameter). One hypothesis to explain these observations is seismic reverberation after impact events. We used a combination of seismic and geomorphic modeling to analyze the response of regolith-covered topography, particularly craters, to impact-induced seismic shaking. Applying these results to a stochastic cratering model for the surface of Eros produced good agreement with the observed size-frequency distribution of craters, including the paucity of small craters.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Richardson, James E -- Melosh, H Jay -- Greenberg, Richard -- New York, N.Y. -- Science. 2004 Nov 26;306(5701):1526-9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Lunar and Planetary Laboratory, University of Arizona, Tucson, AZ 85721, USA. jrich@lpl.arizona.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15567856" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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