ISSN:
1612-1112
Keywords:
Column liquid chromatography
;
Chiral stationary phase
;
Resolution of amino acid derivatives
;
Enantioseparation by HPLC
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary A chiral stationary phase for the separation of some D-and L-amino acid derivatives using a new resolving agent is described. The enantiomeric resolution was accomplished by normal phase high-performance liquid chromatography. The support was easily prepared by coating an epoxy polymer of L-valinamide on aminopropylsilanized macroporous silica. The influence of subambient temperatures on the enantioselectivity was also examined.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02261064
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