ISSN:
1612-1112
Keywords:
Column liquid chromatography
;
Micellar electrokinetic chromatography (MEKC)
;
Oral contraceptives
;
Ethinylestradiol
;
Gestodene
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary A micellar electrokinetic chromatographic method is presented which permits quantification of ethinylestradiol and gestodene in pharmaceutical products. Separation was carried out at 25°C and 25 KV, using a 20 mM borate buffer (pH 9.2), 15 mM sodium dodecylsulfate in 30% acetonitrile-water (v/v). Under these conditions analyses were carried out in 7 min. Four different oral contraceptives were analysed and the results compared favourably with those of a reference liquid chromatographic method.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02467189
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