ISSN:
1420-9071
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Medizin
Notizen:
Summary Treating VY/WfL-A vy /a mice with 5α-androstan-17-one, a mammalian glucose-6-phosphate dehydrogenase inhibitor, prevented the mice from becoming obese. The weight difference between treated and controlA vy /a mice was mainly due to a decreased accumulation of triacylglycerol. The compound did not suppress appetite, had no detectable toxicity and did not affect the lipogenesis rates in the liver and carcass. The weight-controlling effect of 5α-androstan-17-one inA vy /a mice was reversible upon withdrawal of treatment.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF02034660
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