ISSN:
1573-4943
Keywords:
cross-linking
;
hemoglobin
;
maleimides
;
hydroxysuccinimide esters
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract A series of chemical bifunctional cross-linking reagents, the succinimidyl maleimides, has been synthesized. Using hemoglobin as a model protein, it has been shown that these molecules react rapidly with sulfhydryl groups and more slowly with amino groups. The result is a high degree of specific cross-linking between the intramolecular subunits.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01025358
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