Publication Date:
2015-06-17
Description:
Article mTOR signalling regulates protein synthesis in response to changes in nutrient availability. Chang et al. demonstrate that mTOR can stimulate translation by promoting the shortening of mRNA 3′-untranslated regions, and that expression of ubiquitin ligases is selectively enhanced by this mechanism. Nature Communications doi: 10.1038/ncomms8218 Authors: Jae-Woong Chang, Wei Zhang, Hsin-Sung Yeh, Ebbing P. de Jong, Semo Jun, Kwan-Hyun Kim, Sun S. Bae, Kenneth Beckman, Tae Hyun Hwang, Kye-Seong Kim, Do-Hyung Kim, Timothy J. Griffin, Rui Kuang, Jeongsik Yong
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
Permalink