Publication Date:
2008-12-17
Description:
A central question in developmental biology is whether and how mechanical forces serve as cues for cellular behavior and thereby regulate morphogenesis. We found that morphogenesis at the Arabidopsis shoot apex depends on the microtubule cytoskeleton, which in turn is regulated by mechanical stress. A combination of experiments and modeling shows that a feedback loop encompassing tissue morphology, stress patterns, and microtubule-mediated cellular properties is sufficient to account for the coordinated patterns of microtubule arrays observed in epidermal cells, as well as for patterns of apical morphogenesis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hamant, Olivier -- Heisler, Marcus G -- Jonsson, Henrik -- Krupinski, Pawel -- Uyttewaal, Magalie -- Bokov, Plamen -- Corson, Francis -- Sahlin, Patrik -- Boudaoud, Arezki -- Meyerowitz, Elliot M -- Couder, Yves -- Traas, Jan -- New York, N.Y. -- Science. 2008 Dec 12;322(5908):1650-5. doi: 10.1126/science.1165594.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉INRA, Laboratoire de Reproduction et Developpement des Plantes, 46 Allee d'Italie, 69364 Lyon Cedex 07, France.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19074340" target="_blank"〉PubMed〈/a〉
Keywords:
Arabidopsis/anatomy & histology/cytology/*growth & development
;
Cell Shape
;
Cell Wall/physiology/ultrastructure
;
Cellulose
;
Dinitrobenzenes/pharmacology
;
Meristem/cytology/*growth & development
;
Microfibrils/physiology
;
Microtubules/*physiology/ultrastructure
;
Models, Biological
;
Morphogenesis
;
Plant Epidermis/physiology
;
Plant Shoots/anatomy & histology/cytology/*growth & development
;
Plant Stems/cytology/growth & development
;
Pressure
;
Stress, Mechanical
;
Sulfanilamides/pharmacology
;
Tubulin Modulators/pharmacology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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