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  • 1
    Electronic Resource
    Electronic Resource
    The fine structure of blood cells in the ascidian Perophora viridis (1966)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 119 (1966), S. 305-326 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The fine structure of each of the blood cell types of Perophora viridis has been characterized and strong evidence for localization of vanadium in two of these types is given.There are eight cell types; phagocytes which may contain completely engulfed cells, lymphocytes with a prominant nucleolus and scanty cytoplasm packed with clustered ribosomes, and six other cell types each with distinctive granules. Morula cells contain a central nucleus and cytoplasm filled by wedged bodies, about five of which are seen in section. These bodies contain regularly spaced electron dense foci. Green cells have the same organization but contain bodies which are electron dense throughout. Granular amoebocytes contain many smaller lightly staining oval bodies and much glycogen. Another cell type (probably orange cells of light microscopy) contains numerous granular rounded bodies. Compartment cells have vacuoles containing electron dense particles and signet ring cells have usually one large vacuole which is electron dense lined and may contain electron dense particles. Developmental stages of these cell types show involvement of endoplasmic reticulum and Golgi bodies in granule formation.After glutaraldehyde fixation alone the only extremely electron dense components are particles in the compartment cells and signet ring cells implicating these as sites of vanadium localization, although not excluding other cell types.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051190304
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  • 2
    Electronic Resource
    Electronic Resource
    Fine structure of the developing gastric epithelium of the chick (1971)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 133 (1971), S. 375-386 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The fine structure of the developing gizzard of the chick embryo has been studied to define the sequence of events in cytodifferentiation of the epithelium and to look for morphological evidence of epithelio-mesenchymal interaction. During the fourth day of incubation epithelial cells begin to form mucous secretory granules, later massive glycogen deposits appear, and finally by day 8 numerous cell processes have formed. Tissue was prepared by a number of methods to stain material associated with cell surfaces. At the time induction is presumbably occurring such stainable material is abundant. Epithelial and mesenchymal tissue components when cultured transfilter show no inductive effects and stainable cell surface material is greatly reduced near the epithelium.
    Additional Material: 21 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051330402
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  • 3
    Electronic Resource
    Electronic Resource
    The fine structure of developing bristles in wild type and mutant Drosophila melanogaster (1967)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 122 (1967), S. 367-379 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: In an attempt to understand the factors involved in morphogenesis of a complex cell like a scale or bristle, the fine structure of the normal development of bristle cells in Drosophila melanogaster (Oregon R) has been studied and compared with that of the mutants sn3 and Sb. In the development of the normal bristle rounded bundles of longitudinally oriented fibrils lie just beneath the cell surface at regularly spaced intervals. Fiber bundles constitute about 20% of the cross sectional area. The cytoplasmic surface between these bundles is active in enveloping the nerve fiber associated with the bristle and in sending out cytoplasmic processes associated with which the longitudinally oriented bristle ridges form. Singed bristles are bent and twisted and the fiber bundles are present as flattened bands constituting only about 5% of the cross-sectional area. In Sb mutants the total cross-sectional area of fiber bundle material is the same as that in Oregon R, but fiber bundles are smaller and more numerous, being distributed over the larger surface of this thicker and shorter bristle. They constitute only 7% of the cross-sectional area of the bristle. In Sn3Sb mutants characteristics of each gene are exaggerated and an extremely short, wide, and irregular bristle is formed.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051220406
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  • 4
    Electronic Resource
    Electronic Resource
    Scanning microscopy of collagen in the basement lamella of normal and regenerating frog tadpoles (1976)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 150 (1976), S. 805-823 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The arrangement of collagen fibers over the body surface in the basement lamella of Pseudaeris and Xenopus tadpoles is described. It can be viewed by scanning microscopy after removal of epidermis and basal lamina by trypsin treatment of alcohol fixed tissue. The orthogonal array is modified in regions where fiber direction changes extensively such as the base of the ventral fin or the posterior part of the head. In these regions “exceptional points” in the orthogonal pattern occur, as described by Rosin (1946). The pattern is bilaterally symmetrical. In the region of the nasal opening the orthogonal pattern is replaced by a mat of randomly oriented fibers. In tail regeneration the wound area is marked by aberrant disposition of collagen anteriorly then a mat of randomly disposed fibers followed posteriorly with a sharp transition to the orthogonal pattern of the regenerate. No fiber terminations could be seen in normal or regenerating regions of the lamella.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051500403
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  • 5
    Electronic Resource
    Electronic Resource
    Alignment of desmosomes in stratifying human epidermis (1988)
    Springer
    Cell & tissue research 254 (1988), S. 585-592 
    Details
    ISSN: 1432-0878
    Keywords: Epidermis ; Desmosomes ; Immunocytochemistry ; Fine structure ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Cultured human epithelial cells stained with antibody to desmosomal proteins by indirect immunofluorescence showed linear arrays of desmosomes en face between stratified cells. To confirm that an extensive linear pattern existed on the cell surface, subconfluent cultures were viewed using scanning electron microscopy. Aligned arrays of blunt protrusions lying parallel to each other and extending in the direction of the long axis of the cell were observed on the surface of groups of superficial cells in intact cultures. That this pattern was indeed related to desmosomal distribution was verified by transmission microscopy of thin sections cut in a plane between the upper and lower surfaces of flattened stratified cells to view desmosomes directly. A similar arrangement of desmosomes was seen in intact tissue, using epidermal sheets separated from newborn foreskin. The same pattern found in flattened cells was sometimes apparent in more rounded basal cells where the cytoplasm was beginning to extend. Since desmosomal plaques are associated with keratin filaments, the alignment of desmosomes must occur in association with cytoskeletal changes as cells become flattened toward the distal epithelial surface. The primary initiation of desmosomal alignment remains to be investigated. However, the present findings demonstrate an increasingly regular membrane-cytoskeletal spatial interaction as stratified epithelial cells of skin mature.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00226508
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  • 6
    Electronic Resource
    Electronic Resource
    Fusion of epithelial sheets as seen in formation of the chick amnion (1989)
    Springer
    Cell & tissue research 257 (1989), S. 141-147 
    Details
    ISSN: 1432-0878
    Keywords: Amnion ; Epithelial fusion ; Cell-death ; Domestic fowl
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Fusion of the amniotic folds over the chick embryo provides an example of epithelial fusion in which one group of ectodermal cells appears to contribute to traction and a second group appears to respond by moving to the midline, becoming internalized and degenerating. Neutral red staining of living embryos and transmission electron microscopy indicate that a patch of dying cells is present in the fusion region. Scanning electron microscopy shows that ectoderm cells at the rim of the amniotic folds are cylindrical in shape with long axes oriented parallel to the rim. These cells have a smooth surface, but show increasing amounts of blebbing toward the midline. Characteristically, a globular region of rounded cells showing extreme blebbing is present at the midline. Just anterior to the globular region, flattened cells are present on the surface with many taut cellular processes. Orientation of ectodermal cells around the region of fusion suggests that traction is exerted from these flattened cells. When treated with cytochalasin D, posterior progression of the zone of fusion is blocked. Also, the flattened cells anterior to the globular region round up, revealing many elongated, anteriorly-directed cytoplasmic processes presumably leading to sites of original attachment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00221644
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  • 7
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    Fusion of epithelial sheets as seen in formation of the chick amnion (1989)
    Springer
    Details
    Publication Date: 1989-07-01
    Print ISSN: 0302-766X
    Electronic ISSN: 1432-0878
    Topics: Biology , Medicine
    Published by Springer
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  • 8
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    Alignment of desmosomes in stratifying human epidermis (1988)
    Springer
    Details
    Publication Date: 1988-12-01
    Print ISSN: 0302-766X
    Electronic ISSN: 1432-0878
    Topics: Biology , Medicine
    Published by Springer
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  • 9
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    Is there an instance of Steinberg's “site frequency model”? (1977)
    Elsevier
    Details
    Publication Date: 1977-04-01
    Print ISSN: 0022-5193
    Electronic ISSN: 1095-8541
    Topics: Biology
    Published by Elsevier
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  • 10
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    Scanning electron microscopic visualization of collagen fibers in embryonic chick skin (1976)
    Elsevier
    Details
    Publication Date: 1976-01-01
    Print ISSN: 0012-1606
    Electronic ISSN: 1095-564X
    Topics: Biology
    Published by Elsevier
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