ISSN:
0009-2940
Keywords:
Chromatographic separation
;
[n]Paracyclophanecarboxylic acid derivatives
;
CD spectra
;
Absolute configuration
;
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Synthesis of Medium and Large Rings, XXVII1. - Chromatographic Separation of the Enantiomeric 3.6-Heptanophthalides. - A Contribution to the Problem of the Absolute Configuration of [nJ Paracyclophanecarboxylic AcidsThe partial chromatographic separation of the racemic title compound 1 (ee = 40%) was achieved on triacetylcellulose with ethanol using a recycling technique. Comparison of the CD spectra of (+)22365-1 with (+)22365-2 leads to the absolute configuration (P) for both compounds. This assignment is of interest in view of earlier configurational assignments for [n]paracyclophanecarboxylic acids.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19901230638
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