ISSN:
1432-072X
Keywords:
Adenosine pentaphosphate
;
Guanosine tetraphosphate
;
pppApp
;
ppGpp
;
Nucleoside polyphosphate
;
Spore germination
;
Streptomyces
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract Exogenous addition of adenosine- and guanosine 5′-(di- and tri) phosphate 3′-diphosphate (pppApp, ppApp, pppGpp and ppGpp) at the concentration of 0.5 mM inhibits spore germination of Streptomyces galilaeus ATCC 31133. This reversible inhibitory effect appeared to be at the transcriptional level, and also depends on the phase of spore germination; pppApp inhibited more strongly RNA synthesis in the period of the germ tube emergence than the early stage of germination. No inhibitory effect was observed with normal purine and pyrimidine nucleosides, nucleotides, pApp, pGpp, cyclic AMP and pyrophosphoric acid at the concentration of 0.1–1.0 mM.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00446889
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