ISSN:
1435-604X
Keywords:
Keywords: Cell proliferation; Dog tumour cell; He-Ne laser; Photobiology; Photodynamic therapy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
,
Physics
,
Technology
Notes:
Abstract. The effects of laser light on the cellular proliferation have been extensively characterised. Low-power laser sources, such as the helium–neon (He-Ne) laser irradiation with a wavelength of 632.8 nm, have been found to produce photobiological and photodamaging effects with evidence of interference with cell proliferation functions. The present study has investigated the in vitro effect of He-Ne laser irradiation on the proliferative action of dog tumour cells in culture. Dose–response studies showed that repeated He-Ne irradiation (irradiance 12.8 mW/cm2) once a day for 4 consecutive days in a dose range between 0.13 and 2.08 J/cm2 significantly increased with increasing energy density up to a laser dose of 0.26 J/cm2, whereas at 〉1.04 J/cm2, the cell proliferation decreased with increasing energy densities. It is concluded that the application of He-Ne laser irradiation at energy densities ranging from 0.13 J/cm2 to 2.08 J/cm2 produced different effects on cell proliferation in dog tumour cells in culture.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s101030050068
Permalink