ISSN:
1573-8221
Keywords:
melatonin
;
lifespan
;
geroprotector
;
Drosophila melanogaster
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract The lifespan ofD. melanogaster treated with melatonin in a concentration of 0.08% at the stage of development is studied. The geroprotective effect of melatonin is the most obvious (up to 12–18%) in comparison with controls with a short lifespan; if the controls' lifespan was relatively long, the hormone exerts negligible or toxic effect shortening the lifespan by up to 10%. Antioxidant mechanism of geroprotective effect of melatonin is discussed in light of the concept of fluctuations in the lifespan in successiveD. melanogaster generations.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02433110
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