ISSN:
1574-6968
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Biology
Notes:
Using chemical analysis and 13C-nuclear magnetic resonance (NMR) spectroscopy, capsular polysaccharide purified from culture supernatants of a strain of Pasteurella haemolytica serotype A2 was shown to consist of a (2 → 8)-α-linked polymer of N-acetylneuraminic acid. This is identical to the capsular polysaccharides of Neisseria meningitidis group B and Escherichia coli K1, and is known as colominic acid. Polymer isolated from a second strain was contaminated with α-1,4-linked dextran. The known poor immunogenicity of these two polymers explains the failure by others to produce effective extract vaccines for this important ovine pathogen.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1574-6968.1987.tb02293.x
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