ISSN:
1573-739X
Keywords:
Antibiotics
;
Bacteria
;
Clinical trials
;
Costs and cost analysis
;
Drug utilization
;
Infection
;
Multiple trauma
;
Selective digestive decontamination
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract A double-blind randomized placebo-controlled study was carried out to evaluate the efficacy and the cost of selective digestive decontamination (SDD) to prevent nosocomial pneumonia in multiple-trauma patients. Nosocomial infections, particularly pneumonia, were more frequent in the placebo group. The most common infectious agent wasStaphylococcus: Staphylococcus aureus in the placebo group andStaphylococcus epidermidis in the SDD group. Methicillin-resistantStaphylococcus epidermidis was detected more often in the SDD group. No methicillin-resistantStaphylococcus aureus was observed in this study. Fewer patients in the SDD group required antibiotherapy. SDD resulted in a saving of about 41% in drug expenditure.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01875552
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