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  • 1
    ISSN: 1467-9787
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geography , Economics
    Notes: . Associative memory techniques are drawn from the artificial intelligence literature, and have demonstrated considerable utility for parameter identification in dynamical systems. Previous turning point forecasts constructed by LeSage are compared to forecasts generated by associative memories and simple autoregressive models. Both the associative memories and the autoregressions perform as well or better than the more complicated econometric procedures described by LeSage, with the exception of West and Harrison's (1989) dynamic linear model specification. Extensions are suggested.
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 45 (1973), S. 2009-2014 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-9686
    Keywords: Hemodynamics ; Myocardial contraction ; Wall shear stress ; Flow in a curved tube ; Artery: coronary ; Time-varying curvature ; Rheology: curved tubes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract The flow through a curved tube whose radius of curvature varies with time was studied in order to better understand flow patterns in coronary arteries. A computational flow model was constructed using commercially available software. The artery model featured a uniform circular cross section, and the curvature was assumed to be constant along the tube, and in one plane. The computational model was verified with the use of a dynamically similar in vitro apparatus. A steady uniform velocity was prescribed at the entrance at a Reynolds number of 300. Two sets of results were obtained: one in which the curvature was held constant at the mean, maximum and minimum radii of curvature (quasistatic), and another in which the curvature was varied sinusoidally in time at a frequency of 1 Hz (dynamic). The results of the dynamic analysis showed that the wall shear rates varied as much as 52% of the static mean wall shear rate within a region of 10 tube diameters from the inlet. The results of the dynamic analysis were within 6% of the quasistatic predictions. Realistic modeling of the deforming geometry is important in determining which locations in the coronary arteries are subjected to low and oscillating wall shear stresses, flow patterns that have been associated with atherogenesis. © 1998 Biomedical Engineering Society. PAC98: 8745Hw, 8710+e
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Annals of biomedical engineering 28 (2000), S. 386-398 
    ISSN: 1573-9686
    Keywords: Stents ; Vascular prosthesis ; Computational fluid dynamics ; Restenosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract Local flow alterations created by a metallic stent in a simulated coronary artery were studied to compare the hemodynamic effects of two different stent geometries. Dye injection flow visualization and computational fluid dynamics were used. Resting and exercise conditions were studied. Flow visualization using the dye injection method provided a qualitative picture of stent hemodynamics while the computational approach provided detailed quantitative information on the flow next to the vessel wall near the intersections of stent wires. Dye injection visualization revealed that more dye became entrapped between the wires where the wire spacing was smallest. The dye washout times were shorter under exercise conditions for both wire spacings tested. The computational results showed that stagnation zones were continuous from one wire to the next when the wire spacing was small. Results from greater wire spacing (more than six wire diameters) showed that the stagnation zones were separate for at least part of the cardiac cycle. The sizes of the stagnation zones were larger under exercise conditions, and the largest stagnation zones were observed distal to the stent. These studies demonstrate that stent geometry has a significant effect on local hemodynamics. The observation that fluid stagnation is continuous in stents with wire spacings of less than six wire diameters may provide a criterion for future stent design. © 2000 Biomedical Engineering Society. PAC00: 8719Uv, 8719Hh, 8780-y
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  • 5
    ISSN: 1573-1480
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract Equations of fish yield in lakes as a function of mean annual air temperature have been published for lake whitefish, northern pike, and walleye. Using the contouring and modelling features of a geographic information system (Tydac Technologies' SPANS), we prepared maps of (i) species distribution, (ii) mean annual air temperature, and (iii) temperature increases predicted by the Goddard Institute for Space Studies' global climate model (GISS-GCM). We combined these maps with the yield equations for the three study species to form a regional model predicting the spatial distribution of yield capability in eastern Canada with and without climate change. The GISS-GCM predicts temperature increases of 2.5 to 7.7 °C (mean = 4.5 °C) in eastern Canada, midway between the values predicted by two other GCMs considered. The regional model predicts a substantial spatial re-distribution of fishery capabilities. Areas now supporting high yields become marginal and areas at the margin of, or outside, the current species range become ‘optimal’. Without efforts to prevent temperature increases or large artificial efforts to redistribute preferred fish species, Canadian freshwater fisheries will suffer major disruptions given the temperature increases predicted by the GISS-GCM.
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  • 6
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The anionic polymerization of a variety of secondary alkyl crotonates and related monomers initiated by fluorenyllithium (complexed with tetrahydrofuran) in toluene at -78°C. is reported. No crystallinity could be developed in any of the samples, and nuclear magnetic resonance was uniformative about possible tacticity. The polymerization techniques were ineffective when applied to n-alkyl esters. Polymer was obtained from isopropyl cinnamate and N,N-dimethyl crotonamide, but not from isopropyl thiocrotonate or isopropyl 2-pentenoate. The physical properties of injectionmolded specimens of polymers of isopropyl, s-butyl and cyclohexyl crotonate were examined in some detail; the polymers exhibited a desirable combination of high service temperatures and good impact resistance for a vinyl homopolymer but were extremely difficult to mold. Poly(isopropyl crotonate) had a heat distortion temperature of 125°C. at 85 psi, a notched Izod impact of 2.4 ft.-lb./in. of notch, and a flexural modulus of 274,000 psi.
    Additional Material: 3 Tab.
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Annals of biomedical engineering 21 (1993), S. 45-49 
    ISSN: 1573-9686
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Conclusion The numerical solution of Womersley flow can provide important physical insights to the student of Biofluid dynamics. This computer program is less than 70 lines and can be entered rapidly without extensive knowledge of Mathematica. Through manipulations, the effect of changes in the unsteadiness parameter, Reynolds number, and waveform shape on the pulsatile hemodynamics in straight tubes, can be explored. The exercise reinforces the importance of unsteady forces on the complex processes of physiologic flow and illustrates the usefulness of computers in fluid mechanics analyses.
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  • 8
    ISSN: 1573-9686
    Keywords: Endothelium ; Shear stress ; Cyclic stretch
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract The proposal of the role of mechanical forces as a localizing factor of atherosclerosis has led many researchers to investigate their effects on vascular endothelial cells. Most previous efforts have concentrated on either the fluid shear stress, which results from the flow of blood, or the circumferential “hoop” stretch, which results from the expansion of the artery during the cardiac cycle. In fact, arterial endothelial cells are subjected to both fluid shear stress and cyclic hoop stretchin vivo. Therefore, a more complete investigation of mechanical phenomena on endothelial cell behavior should include both kinds of mechanical stimuli. This study was undertaken to design an experimental apparatus that could subject cultured vascular endothelial cells to simultaneous physiologic levels of both shear stress and cyclic hoop stretch. The experimental apparatus consists of four cylindrical elastic tubes so that the following conditions may be studied: (a) static conditions; (b) shear stress only; (c) hoop stretch only; and (d) shear stress and hoop stretch. In order to establish the functional capabilities of the apparatus, bovine pulmonary artery endothelial cells were cultured in the tubes, and their morphology and f-actin structur were observed with confocal microscopy. The cells remained healthy and attached to the walls throughout the 24 hr experiment. Preliminary results indicated that the alignment of endothelial cells subjected to shear stress was significantly enhanced by the addition of hoop strain.
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  • 9
    ISSN: 0003-3146
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: When poly(methyl methacrylate) films containing UV absorbers are exposed to UV light, the absorbers undergo photodegradation resulting in loss of absorbance. If the data extend for less than one half-life, both zero and first order kinetic treatment give fairly linear fits, but the rate constants so derived are dependent on the initial absorbance of the films. When the zero order rate constants are corrected to account for the higher rate of degradation near the surface compared with the bulk that occurs in highly absorbing films, consistent “infinite absorption” zero order rate constants are derived. The inhomogeneous degradation is due to only the highly absorbed, higher energy light contributing significantly to the degradation. For the benzophenone and benzotriazole classes of absorber, at least 65% of the degradation is due to light with wavelengths 〈 350 nm. Structural variations generally caused only small differences in the rates of degradation of these classes of absorbers unless the substitutions disrupted the intramolecular hydrogen bonds that are critical for stability. If the hydrogen bond is weakened, the absorber is less stable.
    Additional Material: 3 Ill.
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  • 10
    Publication Date: 1962-08-01
    Print ISSN: 0021-8979
    Electronic ISSN: 1089-7550
    Topics: Physics
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