Publication Date:
2018-08-28
Description:
HIV-1 intron-containing RNA expression induces innate immune activation and T cell dysfunction HIV-1 intron-containing RNA expression induces innate immune activation and T cell dysfunction, Published online: 27 August 2018; doi:10.1038/s41467-018-05899-7 Type I Interferon is thought to be a driving force for immune activation and T cell exhaustion during HIV infection. Here the authors show that intron-containing HIV RNA induces innate immune activation resulting in associated T cell dysfunction.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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