Publication Date:
2014-10-30
Description:
Key Points XIAP deficiency selectively diminishes BCL10-mediated innate responses and impairs the ability of the host to control specific microbes. The selective innate immunodeficiency in the XIAP-deficient host leads to the persistent presence of specific pathogens and excess inflammation.
Print ISSN:
0006-4971
Electronic ISSN:
1528-0020
Topics:
Biology
,
Medicine
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