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  • 1
    Call number: M 09.0081
    In: Lecture notes in computer science
    Description / Table of Contents: This tutorial book presents an augmented selection of the material presented at the GI-Dagstuhl Research Seminar on Human-Centered Visualization Environments, HCVE 2006, held in Dagstuhl Castle, Germany in March 2006. The 8 tutorial lectures presented are the thoroughly cross-reviewed and revised versions of the summaries and findings, presented and discussed at the seminar. After an introduction to human-centered visualization environments the fundamental principles and methods in that area are shown such as human-centered aspects, interacting with visualizations, visual representations, as well as challenges and unsolved problems. The book is concluded with lectures on domain-specific visualization describing geographic visualization, algorithm animation, and biomedical information visualization.
    Type of Medium: Monograph available for loan
    Pages: XIX, 403 S. , Ill., graph. Darst. , 235 mm x 155 mm
    ISBN: 3540719482 , 978-3-540-71948-9
    Series Statement: Lecture notes in computer science 4417 : Tutorial
    Location: Upper compact magazine
    Branch Library: GFZ Library
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Archive for rational mechanics and analysis 76 (1981), S. 193-246 
    ISSN: 1432-0673
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    The visual computer 14 (1998), S. 83-94 
    ISSN: 1432-2315
    Keywords: Key words: Volume visualization ; Scientific visualization ; Medical imaging ; Shadow Z-buffer ; Shadow map
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Z -buffer technique for fast and efficient shadow generation. Volumetric data contain information about the grid points only. Such data do not provide surface information that could be projected immediately onto the shadow map. To solve this problem, we have implemented two techniques. The first uses a modified adaptive version of the well-known marching cubes algorithm for the special characteristics of medical data sets. The algorithm uses material properties for a precise representation of object boundaries, generating volumetric objects quickly and effectively. There are two representations of the same data set: we use a view-independent approximation to display shadows and the original representation of the volume for object visualization in full precision. The second algorithm uses a ray-tracing approach to create shadow maps. The same routine is used for object rendering, but is restricted to depth-value generation. Semitransparent objects are handled by storing an intensity profile in addition to the depth value.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1436-5073
    Keywords: molecular ion implantation ; silicon nitride layers ; resonant nuclear reaction analysis ; non-Rutherford RBS ; nitrogen depth profile
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract 15N2 + molecular ions were implanted with 10keV (j=10 μA/cm2) under high vacuum conditions close to room temperature in 〈100〉 silicon (c-Si) to study the13N depth distributions, particularly the dependence of peak concentration and dose on the ion fluence. The analysis were performed by the resonant nuclear reaction15N(p, αγ)12C(NRA). A maximum peak concentration of 65 at.% was measured. Thin stoichiometric silicon nitride layers with a thickness of approx. 20 nm (15 at.% nitrogen at the specimen surface) were produced by this low-energy implantation of15N2 + ions with an ion fluence of 1.5·1017 ions/cm2. NRA analysis of 38 keV15N2 + and 19keV15N+ ion implantations were performed to compare the15N depth distributions. No significant changes in the depth distributions are measured, that means, the molecular15N2 + ions are already disintegrated passing the very first atomic layers of the sample during implantation. Non-Rutherford RBS with4He+ ions and 3.45 MeV was performed in order to confirm the results obtained by NRA.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1436-5073
    Keywords: ion implantation ; silicon nitride layers ; TEM analysis ; resonant nuclear reaction analysis ; nitrogen depth profile
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Thin silicon nitride (SiN x ) layers with the stoichiometric N/Si ratio of 1.33 in the maximum of the concentration depth distributions of nitrogen were produced by implanting 10 keV15N 2 + in 〈100〉 silicon at room temperature under high vacuum conditions. The depth distribution of the implanted isotope was measured by resonance nuclear reaction analysis (NRA), whereas the layer structure of the implanted region and the geometrical thickness of the layers were characterised by high resolution transmission electron microscopy (TEM). SiN x layers with a thickness of about 30 nm were determined by NRA. Channeling Rutherford backscattering spectrometry was used to determine the disorder in the silicon substrate. Sharp interfaces of a few nanometers between the highly disordered implanted region and the crystalline structure of the substrate thickness were observed by TEM. The high thermal stability of SiN x layers with N/Si ratios from under to over stoichiometric could be shown by electron beam rapid thermal annealing (1100 °C for 15 s, ramping up and down 5 °C/s) and NRA.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1424
    Keywords: blood-brain barrier ; inward-rectifying K− channels ; angiotensin II ; arginine-vasopressin ; guanosine 5′-[γ-thio]triphosphate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary Cerebral capillaries from porcine brain were isolated. and endothelial cells were grown in primary culture. The whole-cell tight seal patch-clamp method was applied to freshly isolated single endothelial cells, and cells which were held in culture up to one week. With high K+ solution in the patch pipette and in the bath we observed inward-rectifying K+ currents, showing a time-dependent decay in part of the experiments. Ba2+ (1–10mm) in the bath blocked this current, whereas outside tetraethylammonium (10mm) decreased the peak current but increased the steady-state current. Addition of 1 μm of angiotensin II or of arginine-vasopressin to the extracellular side caused a time-dependent inhibition of the inward-rectifying K+ current in part of the experiments. Addition of 100 μm GTP[γ-S] to the patch pipette blocked the K+ inward rectifier. In cell-attached membrane patches two types of single inward-rectifying K+ channels were observed, with single channel conductances of 7 and 35 pS. Cell-attached patches were also obtained at the antiluminal membrane of intact isolated cerebral capillaries. Only one type of K+ channel withg=30 pS was recorded. In conclusion, inwardly rectifying K+ channels, which can be inhibited by extracellular angiotensin II and arginine-vasopressin, are present in cerebral capillary endothelial cells. The inhibition of this K+ conductance by GTP[γ-S] indicates that G-proteins are involved in channel regulation. It is suggested that angiotensin II and vasopressin regulate K+ transport across the blood-brain barrier, mediating their effects via G-proteins.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0878
    Keywords: γ-Glutamyl transpeptidase ; Cerebral capillaries ; Blood-brain barrier ; Cell culture ; Pig
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Endothelial cells were isolated with high viability (〉93%) from porcine brain capillaries by Percoll gradient centrifugation after purely enzymatic digestion. Primary cultures were grown to confluent cell monolayers and quantitated for the activity of γ-glutamyl transpeptidase. The γ-glutamyl transpeptidase activity starts from a high enzymatic level, decreases with time in culture to about 15% of the initial value, and remains constant at this level after day 10 in culture. The activity progression depends on surface conditions. In the presence of collagen, an exponential decrease starts immediately after seeding, with a time constant of 70±10h. In the absence of collagen, γ-glutamyl transpeptidase activity first decreases on day 1 after plating, recovers to the initial value on day 2 and 3 and afterwards declines exponentially to a low and constant activity level. Ethanol added to the cell culture at a time when low constant activity is reached, reactivates the γ-glutamyl transpeptidase to 30% of the initial value.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-136X
    Keywords: Arterioles ; Vasomotion ; Angiotensin II ; Vasopressin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The effects of intracerebroventricular (icv) injections of 10 ng angiotensin II (ANG II) on mean arteriolar diameter and spontaneous arteriolar vasomotion were studied in subcutaneous tissue of conscious, restrained hamsters, using the skin fold window chamber preparation. Angiotensin II caused a significant decrease in mean arteriolar diameter which was associated with a significant elevation in the amplitude of vasomotion. The frequency of vasomotion did not change significantly. The central ANG II-induced effects on arteriolar vasomotion were not significantly altered by continuous intravenous (iv) infusion of hexamethonium (1 mg · kg−1 · min−1). In contrast, iv bolus injection of the vascular vasopressin receptor antagonist d(CH2)5Tyr(Me)AVP (10 μg · kg−1) 5 min prior to icv injection of ANG II significantly attenuated the effects of the neuropeptide on mean arteriolar diameter and the amplitude of vasomotion. These data indicate that central ANG II stimulation enhances arteriolar vasomotion in peripheral subcutaneous tissue of conscious hamsters and that this effect may be mediated by release of vasopressin.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-136X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The effects of intracerebroventricular (icv) injections of angiotensin II (ANG II) on water intake, blood pressure, heart rate, and plasma arginine-vasopressin (AVP) concentration were studied in chronically instrumented adult male Syrian golden hamsters (Mesocricetus auratus). Furthermore, the effects of pharmacological ganglionic blockade, and of vascular AVP receptor blockade, on central ANG II-induced cardiovascular responses were investigated. ANG II (1, 10, and 100 ng, icv) elicited dose-dependent increases in water intake and arterial blood pressure. Heart rate showed a biphasic response with a short initial non dose-dependent tachycardic and a subsequent longer lasting bradycardic phase. Plasma AVP concentration was increased two and a half fold with 100 ng ANG II icv. Both ganglionic blockade and vascular AVP receptor blockade significantly attenuated the central ANG II-induced pressor response. The tachycardic phase of the heart rate response was abolished by ganglionic blockade and the bradycardic phase was significantly diminished by AVP receptor blockade. The results support the hypothesis that brain ANG II may participate in the central control of body fluid volume and in central cardiovascular regulation in conscious hamsters.
    Type of Medium: Electronic Resource
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  • 10
    Publication Date: 2023-12-20
    Description: The Helmholtz Association funded the ""Large-Scale Data Management and Analysis"" portfolio theme from 2012-2016. Four Helmholtz centres, six universities and another research institution in Germany joined to enable data-intensive science by optimising data life cycles in selected scientific communities. In our Data Life cycle Labs, data experts performed joint R&D together with scientific communities. The Data Services Integration Team focused on generic solutions applied by several communities.
    Keywords: QA75.5-76.95 ; Data Science ; Datenlebenszyklus ; Datenmanagement ; data management ; data analysis ; data science ; Big Data ; Datenanalyse ; data life cycle ; bic Book Industry Communication::U Computing & information technology::UY Computer science
    Language: English
    Format: image/jpeg
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