ISSN:
0021-9304
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
,
Technology
Notes:
Glass ceramic implants containing 45% SiO2 with a Ca/P ration of 5 become firmly fixed to bone when placed in a cortical defect of an intact rat femur. The addition of fluoride ions to the implant prevents this fixation. The most significant difference between the two compositions is in their solubilites. The presence of high local concentractions of Ca and PO4 ions at the interface of the soluble non-fluoride containing implant, could account for the deposition of bone at its surface.It is not felt from these studies, however, that this model will be usable as a mass screening tecunique for evaluating materials variables. It is felt that other less laborous in vitro systems need to be devised.
Additional Material:
8 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jbm.820060312
Permalink