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  • 1
    Keywords: Medicine Research. ; Biology Research. ; Genetics. ; Bioinformatics. ; Biomedical Research. ; Genetics and Genomics. ; Bioinformatics.
    Description / Table of Contents: Chapter 1_Introduction to Pulmonary Diseases and OMICS approaches -- Chapter 2_Obstructive Pulmonary Diseases -- Chapter 3_COPD (Chronic Obstructive Pulmonar Diseases) -- Chapter 4_ Asthma -- Chapter 5_Other obstructive airway diseases like Bronchiectases, Focal airway narrowing -- Chapter 6_Restrictive Pulmonary Diseases (Common qualities and features with examples) -- Chapter 7_Interstitial Pulmonary fibrosis (IPF) -- Chapter 8_Sarcoidosis -- Chapter 9_ Other restrictive airway diseases like pneumonitis, pleural thickening -- Chapter 10_Vascular Diseases -- Chapter 11_Pulmonary hypertension -- Chapter 12_Pulmonary edema -- Chapter 13_ Other vascular diseases like Pulmonary Edema, Cor Pulmonale -- Chapter 14_Infectious Diseases -- Chapter 15_Tuberculosis -- Chapter 16_Cystic fibrosis -- Chapter 17_Pneumonia, COVID-19 and others -- Chapter 18_Neoplastic Diseases/Lung Cancer.
    Abstract: This book comprehensively reviews various omics approaches like genomics, proteomics, transcriptomics, and metabolomics for understanding pulmonary disease at molecular and systems levels. The initial chapters present the pathogenesis of major pulmonary diseases, namely, obstructive diseases, restrictive diseases, vascular diseases, infectious diseases, and neoplastic carcinoma. The book chapters provide current information about the role of the microbiome and applications of medical imaging, bioinformatics tools, and databases for diagnosis and designing treatment strategies against complex lung diseases. Further, the book discusses omics technologies to identify biomarkers for the early diagnosis and prognosis of pulmonary diseases. Finally, the book elucidates the multi-omics approaches and data integration using mathematical modeling for insights into the disease etiology towards improving the prognostics and predictive accuracy of disease phenotypes.
    Type of Medium: Online Resource
    Pages: XIII, 405 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819935055
    DDC: 610.72
    Language: English
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  • 2
    Publication Date: 2021-02-16
    Description: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of coronavirus induced disease-2019 (COVID-19), is a type of common cold virus responsible for a global pandemic which requires immediate measures for its containment. India has the world’s largest population aged between 10 and 40 years. At the same time, India has a large number of individuals with diabetes, hypertension and kidney diseases, who are at a high risk of developing COVID-19. A vaccine against the SARS-CoV-2, may offer immediate protection from the causative agent of COVID-19, however, the protective memory may be short-lived. Even if vaccination is broadly successful in the world, India has a large and diverse population with over one-third being below the poverty line. Therefore, the success of a vaccine, even when one becomes available, is uncertain, making it necessary to focus on alternate approaches of tackling the disease. In this review, we discuss the differences in COVID-19 death/infection ratio between urban and rural India; and the probable role of the immune system, co-morbidities and associated nutritional status in dictating the death rate of COVID-19 patients in rural and urban India. Also, we focus on strategies for developing masks, vaccines, diagnostics and the role of drugs targeting host-virus protein-protein interactions in enhancing host immunity. We also discuss India’s strengths including the resources of medicinal plants, good food habits and the role of information technology in combating COVID-19. We focus on the Government of India’s measures and strategies for creating awareness in the containment of COVID-19 infection across the country.
    Electronic ISSN: 1664-8021
    Topics: Biology , Medicine
    Published by Frontiers Media
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