ISSN:
1434-1948
Keywords:
Cyclizations
;
Cross-coupling
;
Ab initio calculations
;
Titanium
;
Metallacycles
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Reactions of Cp2Ti(CO)2 (3) with two equivalents of α,β-unsaturated ketones 4 yield the novel titana-2,9-dioxacyclonona-3,7-dienes 5. Cross-coupling of 3 with two different ketones 4 and 6to give 7 can be achieved under certain reaction conditions. Hydrolysis of 5 or 7 may generate diketones 9, cyclopentanols 10/11, or cyclopentenes 12/13, depending on substituents and conditions. The X-ray crystal structure of 5a, the first nine-membered bis(η5-cyclopentadienyl)-substituted titanaheterocycle containing carbon, is presented. Ab initio calculations were performed for 5a and for titana-2-oxacyclopentene 1, a conceivable intermediate in the coupling reaction.
Type of Medium:
Electronic Resource
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