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  • 1
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    In:  Terra Nova, Philadelphia, Wiley, vol. 3, no. 8, pp. 607-618, pp. 1060, (ISSN: 1340-4202)
    Publication Date: 1991
    Keywords: Plate tectonics ; Tectonics ; Geol. aspects
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  • 2
    Publication Date: 2002-08-17
    Description: In striated muscle, the plasma membrane forms tubular invaginations (transverse tubules or T-tubules) that function in depolarization-contraction coupling. Caveolin-3 and amphiphysin were implicated in their biogenesis. Amphiphysin isoforms have a putative role in membrane deformation at endocytic sites. An isoform of amphiphysin 2 concentrated at T-tubules induced tubular plasma membrane invaginations when expressed in nonmuscle cells. This property required exon 10, a phosphoinositide-binding module. In developing myotubes, amphiphysin 2 and caveolin-3 segregated in tubular and vesicular portions of the T-tubule system, respectively. These findings support a role of the bilayer-deforming properties of amphiphysin at T-tubules and, more generally, a physiological role of amphiphysin in membrane deformation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lee, Eunkyung -- Marcucci, Melissa -- Daniell, Laurie -- Pypaert, Marc -- Weisz, Ora A -- Ochoa, Gian-Carlo -- Farsad, Khashayar -- Wenk, Markus R -- De Camilli, Pietro -- CA46128/CA/NCI NIH HHS/ -- NS36251/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 2002 Aug 16;297(5584):1193-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Cell Biology and Howard Hughes Medical Institute, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06510, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12183633" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; CHO Cells ; Caveolin 3 ; Caveolins/metabolism ; Cell Differentiation ; Cell Line ; Cell Membrane/metabolism ; Cell Membrane Structures/metabolism/*ultrastructure ; Cricetinae ; Dynamins ; Exons ; GTP Phosphohydrolases/metabolism ; Liposomes/metabolism ; Mice ; Microscopy, Electron ; Morphogenesis ; *Muscle Development ; Muscle, Skeletal/metabolism/*ultrastructure ; Nerve Tissue Proteins/chemistry/genetics/*metabolism ; Phosphatidylinositol 4,5-Diphosphate/metabolism ; Protein Isoforms ; Protein Structure, Tertiary ; RNA, Small Interfering ; RNA, Untranslated/metabolism ; Recombinant Fusion Proteins/metabolism ; Transfection
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 2014-12-31
    Description: Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides, located within the intergenic stretches or overlapping antisense transcripts of protein coding genes. LncRNAs are involved in numerous biological roles including imprinting, epigenetic regulation, apoptosis, and cell cycle. To determine whether lncRNAs are associated with clinical features and recurrent mutations...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 4
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 71 (2000), S. 1389-1400 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: After having been in development for many years at the Glenn Research Center (formerly the Lewis Research Center), the national aeronautics and space administration-designed, 30 cm, ring-cusp, xenon ion engine was launched on the Deep Space 1 (DS1) spacecraft on 24 Oct. 1998 from the Kennedy Space Center in Florida. It has since accumulated 2200 h of in-space thrusting at input power levels ranging from 0.52 to 1.96 kW, has successfully enabled the spacecraft to fly by the asteroid Braille in July 1999, and is now thrusting DS1 along a trajectory towards its comet destinations in 2001. The design, assembly, test, integration, and operation of this thruster comprise a unique path of technical determination, artful design choices, persistent engineering and analysis, and mastery of vacuum chamber operations. The testing program over the development years, the assembly and integration periods, and the flight operational period thus far have shown that the project test philosophy of segregating effects against unique causes proved itself most useful. The 8000 h life test, the culmination of the pre-launch ground test plan, not only met its goals but surpassed them with margin. This article will explain the thruster test program from beginning to end, illustrating the technical and programmatic decision making along the way. It will justify the use of engineering models as an inexpensive method of determining answers to key design questions and will explain why testing of the thruster alone only solved a portion of the system operations task. The highlight of the test program proved to be the vacuum firing of the ion engine during the spacecraft's solar thermal vacuum test. A comparison of the preflight data with postflight data shows that high confidence was warranted for executing a successful flight to the asteroid and beyond. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Organometallic Chemistry 353 (1988), S. 393-404 
    ISSN: 0022-328X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    FEBS Letters 10 (1970), S. 125-128 
    ISSN: 0014-5793
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    FEBS Letters 1 (1968), S. 272-274 
    ISSN: 0014-5793
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1573-5060
    Keywords: Malus ; apple ; Pyrus ; pear ; double pollination ; pollination interval ; temperature ; pioneer pollen ; seed set first pollen ; seed set second pollen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary Double pollinations of apple and pear may double the seed production, to which the second pollen can contribute 3 times as many seeds as the first (pioneer) pollen, when the interval between pollinations is long enough (48 h) at low (≃ 10°C) or short enough (7 h) at high (≃ 20°C) temperatures. With shorter or longer intervals, the contribution of the second pollen to seed production diminishes. The dominance of the second pollen was attributed to promotion by the first one, the second pollen probably being optimally stimulated when the tubes of the first have passed about 1/3rd of the style. It is concluded that the effectiveness of the pioneer pollen method to overcome incompatibility, depends on whether the interval between pollinations can be usefully adjusted to both the environmentally (temperature) and inherently determined rate of pollen tube growth of the species.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1573-5060
    Keywords: Pyrus ; pear ; Malus ; apple ; self-incompatibility ; mentor/pioneer pollen ; double pollination ; mixed pollination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary The production of self-seed was investigated in apple and pear with the aid of viable and compatible mentor/ pioneer pollen in relation to the proportion of self-imcompatible pollen present in the pollen cloud. Treatments consisted of mixtures of compatible and self-incompatible pollen at ratios of 1:1, 1:2 and 1:9 applied once or twice or followed by self-pollination. Selfing only, whether once or twice, produced virtually no fruits or seeds, while mixed pollinations did. Generally, fruit set tended to decrease and the self-seed to increase with increasing amounts of self pollen in the pollinations. The pioncer-pollen method (compatible in advance of self pollen) appeared more effective than the mentor pollen method (compatible and self pollen mixed). The use of viable instead of dead mentor/pioneer pollen causes competition for the ovules with the self pollen, but has the advantage that, in addition to some self-seed, other seeds are formed which, e.g. in apple, are necessary to keep the fruits on the tree until harvest. Fruit set was moderately reduced at ratios of compatible pollen to self pollen not exceeding 1:9 with pear and 1:5 with apple which constitute maximal ratios in practice as regards pollinator trees: trees of the main cultivar. In fruit orchards and probably in nature with other species, the interaction between compatible and self pollen may result in more self-seed, and so suggests that inbreeding played a greater part in the evolution of self-incompatible species, than the meager results of articial self-pollination imply.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Euphytica 31 (1982), S. 287-290 
    ISSN: 1573-5060
    Keywords: Lilium ; Malus ; Pyrus ; Rosa ; pollen treatment ; heat resistance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary Pollen of dry apple, pear, lily and rose pollen was heated up to 48 h at a range of temperatures. About half or more than half of the pollen grains survived 48 h at 40 C, 24 h at 50 C, 8 16 h at 60 C. 4 8 h at 70 C, more than one hour at 80 C. and between 10 and 20 min at 90 C. Presumably, pollen able to withstand low humidity is also heat resistant, a property which may be usable to make pollen virus free through heat treatment and perhaps to overcome incompatibility.
    Type of Medium: Electronic Resource
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