Publication Date:
2010-05-15
Description:
The mutation-selection-balance model predicts most additive genetic variation to arise from numerous mildly deleterious mutations of small effect. Correspondingly, "good genes" models of sexual selection and recent models for the evolution of sex are built on the assumption that mutational loads and breeding values for fitness-related traits are correlated. In support of this concept, inbreeding depression was negatively genetically correlated with breeding values for traits under natural and sexual selection in the weevil Callosobruchus maculatus. The correlations were stronger in males and strongest for condition. These results confirm the role of existing, partially recessive mutations in maintaining additive genetic variation in outbred populations, reveal the nature of good genes under sexual selection, and show how sexual selection can offset the cost of sex.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tomkins, Joseph L -- Penrose, Marissa A -- Greeff, Johan -- LeBas, Natasha R -- New York, N.Y. -- Science. 2010 May 14;328(5980):892-4. doi: 10.1126/science.1188013.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Centre for Evolutionary Biology, School of Animal Biology, The University of Western Australia, Nedlands, WA 6009, Australia. jtomkins@cyllene.uwa.edu.au〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20466931" target="_blank"〉PubMed〈/a〉
Keywords:
Alleles
;
Animals
;
Beetles/*genetics/physiology
;
*Breeding
;
Female
;
Genes, Insect
;
Genes, Recessive
;
Genetic Fitness
;
*Genetic Variation
;
Inbreeding
;
Male
;
*Mating Preference, Animal
;
*Mutation
;
Reproduction
;
*Selection, Genetic
;
Sex Characteristics
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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