ALBERT

Description: Abstract 4834 Over the past half century, the course of sickle cell disease has been transformed in the United States through the conduct of rigorous biomedical research and broad application of the results. Universal newborn screening with comprehensive medical care has dramatically reduced death and disability in childhood, and increased the numbers of patients surviving into adulthood. However, access to health care has not kept up with the changing demographics of those affected by sickle cell disease. Health care often becomes fragmented when patients transition from pediatric to adult health care providers. Access to comprehensive care has impeded both conduct of clinical and implementation of research results. To address these needs in this changing environment, HHS Secretary Kathleen Sebelius has charged six agencies of HHS – NIH, CDC, HRSA, FDA, AHRQ and CMS – and the Offices of Minority Health and Planning and Evaluation, to improve the health of people with SCD. The agencies are coordinating their programs and collaborating with the Office of the Secretary, to achieve the following goals:create a comprehensive database of individuals with SCD to facilitate the monitoring of health outcomes and clinical research;improve the care of adults and children through development and dissemination of evidence-based guidelines, which are anticipated in Spring, 2012, with broad implementation plans;identify measures of quality of care for individuals with SCD and incorporate them into quality improvement programs at HHS;increase the availability of medical homes to improve patient access to quality primary and specialty care;provide State Medicaid officials, health care providers, patients, families and advocacy groups with information about resources related to SCD care and treatment;work with the pharmaceutical industry and academic investigators to increase the development of effective treatments for patients with SCD;support research to improve health care for people with SCD;support research to understand the clinical implications of SC trait;engage national and community-based SCD advocacy organizations and experts in ongoing discussions to ensure that issues of importance to persons affected are addressed. Organizational and strategic actions are being taken at each agency to enhance implementation of research advances; provide evidence-based guidelines to families, health care providers, and payers; facilitate new drug development; and provide public health data to impact both the health care delivery and research agendas. The enthusiastic support of the American Society of Hematology and its members is essential for long-term success of this endeavor. Disclosures: No relevant conflicts of interest to declare.

Description: William Faulkner occupied a unique position as a modern writer. Although famous for his modernist novels and their notorious difficulty, he also wrote extensively for the "culture industry," and the works he produced for it—including short stories, adaptations, and screenplays—bore many of the hallmarks of consumer art. His experiences as a Hollywood screenwriter influenced him in a number of ways, many of them negative, while the films turned out by the "dream factories" in which he labored sporadically inspired both his interest and his contempt. Faulkner also disparaged the popular magazines—though he frequently sold short stories to them.To what extent was Faulkner's deeply ambivalent relationship to—and involvement with—American popular culture reflected in his modernist or "art" fiction? Peter Lurie finds convincing evidence that Faulkner was keenly aware of commercial culture and adapted its formulae, strategies, and in particular, its visual techniques into the language of his novels of the 1930s. Lurie contends that Faulkner's modernism can be best understood in light of his reaction to the popular culture of his day. Using Theodor Adorno's theory about modern cultural production as a framework, Lurie's close readings of Sanctuary, Light in August, Absalom! Absalom!, and If I Forget Thee, Jerusalem uncover the cultural history that surrounded and influenced the development of Faulkner's art. Lurie is particularly interested in the influence of cinema on Faulkner's fiction and especially the visual strategies he both deployed and critiqued. These include the suggestion of cinematic viewing on the part of readers and of characters in each of the novels; the collective and individual acts of voyeurism in Sanctuary and Light in August; the exposing in Absalom! Absalom! and Light in Augustof stereotypical and cinematic patterns of thought about history and race; and the evocation of popular forms like melodrama and the movie screen in If I Forget Thee, Jerusalem. Offering innovative readings of these canonical works, this study sheds new light on Faulkner's uniquely American modernism.