Publication Date:
2004-11-16
Description:
Objective: To study the expression character of fibrinolytic factors and its inhibitors in rabbits’ tissues extract. Methods: Tissue plasminogen activator ( tPA ), Plasminogen activator inhibitor-1 ( PAI-1 ), Plasminogen ( Plg ), Plasmin ( Pl ) and α2 Plasmin inhibitor ( α2PI ) were measured by colorimetric assay. Results: The tissues extract in renal, small intestine, lung, brain and spleen showed strong fibrinolytic function, and expressed markedly high activity levels of tPA, Plg and Pl. But striped muscle, tongue and stomach expressed markedly high activity levels of PAI-1 and α2PI, and showed low fibrinolytic character. There were linear correlation between levels of tPA and PAI-1 ( r=−0.8076, P
Print ISSN:
0006-4971
Electronic ISSN:
1528-0020
Topics:
Biology
,
Medicine
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