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  • 1
    Electronic Resource
    Electronic Resource
    Effect of femoral rotation on bone mineral density measurements with dual energy X-ray absorptiometry (1995)
    Springer
    Calcified tissue international 57 (1995), S. 340-343 
    Details
    ISSN: 1432-0827
    Keywords: Bone mineral density ; Femoral rotation ; Precision error
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract Precision in femoral neck scans with dual energy X-ray absorptiometry (DXA) is affected by variability in positioning and subsequent repositioning of the femur for repeated scans. To study the in vitro effect of femoral rotation on the bone mineral density (BMD), four fresh-frozen cadaveric femurs were fixed in a specially designed jig which allows for rotation of the femurs. BMD measurements of the femurs were done in neutral position (0°) i.e., with the femoral neck axis parallel to the surface of the couch and at 15°, 30°, and 45° of internal and external rotation. In vivo precision of the femoral neck scan was determined in five normal male subjects. The scans were first done with the legs positioned using the manufacturer's foot block. Five scans were performed, with repositioning, on the left hip of each subject. The procedure was then repeated with the legs positioned using a custom-designed positioning jig to minimize the rotation of the hips during a scan. In the in vitro study, the femoral neck BMD value was minimum at neutral position (0°) and increased when the femur was rotated internally or externally. In vivo precision error of the femoral neck scan was reduced by almost 50% with the use of the positioning jig when compared with the manufacturer's foot block. Femoral rotation was shown to have a significant effect on BMD measurements, and proper positioning of the femur during a scan can improve precision significantly.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00302069
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  • 2
    Electronic Resource
    Electronic Resource
    Effect of decalcification on bone mineral content and bending strength of feline femur (1995)
    Springer
    Calcified tissue international 56 (1995), S. 78-82 
    Details
    ISSN: 1432-0827
    Keywords: Bone mineral content (BMC) ; Cat ; Decalcification ; Ethylene diaminetetra acetic acid (EDTA) ; Femur
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract The relationships between bone mineral content (BMC), bone calcium, and bone strength were studied in fractionally demineralized feline femurs. In 44 pairs of cat femurs, the right bones were decalcified in ethylene diaminetetra acetic acid (EDTA) to 20%, 40%, 60%, 80%, and 100% of the mineral content of the intact left bone (=control). The bones were then loaded to failure, and maximum strength values were recorded. The data were then used to calculate the percentage strength of the right relative to the left femurs. A correlation coefficient (r) of 0.970 was found between the percentage decalcification and percentage bending strength. A direct relationship (r=0.876) was also observed between the total calcium extracted and total loss in BMC. The EDTA solutions were spot checked for protein content to determine if the organic matrices had been altered by demineralization. Protein was never detected. Nor did the demineralized tissues display histologic evidence of gross microscopic damage. This study has shown that in cat femurs, 20% decalcification led to about 35% loss in bending strength, and 60% decalcification caused 75% loss in strength. These values are significant as they highlight the importance of calcium to the strength of osteopenic bone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00298748
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