Publication Date:
2016-07-17
Description:
Article Arp2/3 complex nucleates branched actin filaments, and is inactive in the absense of activators. Here the authors present a model of Arp2/3 autoinhibition, whereby the Arp3 C-terminal tail acts as a structural switch that blocks movement of Arp2 and Arp3 into an activated filament-like conformation. Nature Communications doi: 10.1038/ncomms12226 Authors: Max Rodnick-Smith, Su-Ling Liu, Connor J. Balzer, Qing Luan, Brad J. Nolen
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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